Multifunctional compounds: smart molecules for multifactorial diseases.
about
BRCA1 functions as a novel transcriptional cofactor in HIV-1 infectionTetrahydroberberine, a pharmacologically active naturally occurring alkaloidHybrid curcumin compounds: a new strategy for cancer treatment.New approaches in the design and development of cannabinoid receptor ligands: multifunctional and bivalent compounds.Rational Modification of the Biological Profile of GPCR Ligands through Combination with Other Biologically Active Moieties.Dual abrogation of MNK and mTOR: a novel therapeutic approach for the treatment of aggressive cancers.An overview of molecular hybrids in drug discovery.Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents.Design of chalcogen-containing norepinephrines: efficient GPx mimics and strong cytotoxic agents against HeLa cells.Hybrid antibiotics - clinical progress and novel designs.Systemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery.Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs.Synthesis and Antiproliferative Activity of Silybin Conjugates with Salinomycin and Monensin.Ligand-based Modeling for the Prediction of Pharmacophore Features for Multi-targeted Inhibition of the Arachidonic Acid Cascade.Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore.Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity.A desirability-based multi objective approach for the virtual screening discovery of broad-spectrum anti-gastric cancer agents.Pyrrole and Fused Pyrrole Compounds with Bioactivity against Inflammatory Mediators.Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells.Molecular Consortia-Various Structural and Synthetic Concepts for More Effective Therapeutics Synthesis.Synthesis of novel perillyl-dihydropyrimidinone hybrids designed for antiproliferative activity
P2860
Q35177820-6EF04EC2-691E-4142-A5E9-FA2E3BF0BF20Q36489400-1DF5EC6D-7F06-420D-AAE2-78551FEDBC24Q38290418-7FBF384F-9705-44A5-9E47-EB7DC4CF8C80Q38395251-289F2F2E-B6DE-42E8-B7F4-4126BFC565C5Q38458891-F1E8E5F4-F0E1-46DB-A9D5-90B145CFC5F4Q38637354-68627AED-DE4F-444B-ABFD-3B006AA34357Q38685830-427BD608-89F1-43BB-A1BC-AFC99B08F281Q38717473-CD1C4B71-79F5-4096-AD44-04870884095DQ38795307-EC52A8B7-C902-4B0E-BB84-540FDBDF6328Q38832367-1FD36EDA-C43C-44BD-9B41-B2A90A457C17Q39169235-B685B58B-2F0F-45CE-8EB4-D4B4D14585A6Q39438767-07210D48-D60B-486F-A4C6-799DF2F2D5EFQ42826454-10B64DD1-2143-4F70-9680-889874EEDFDBQ47678019-BD9C07D2-C537-4268-BE54-1893E59DB689Q48150230-345BB099-4C52-4FEE-909F-63C46FB10A9AQ49887912-BDF2938A-EBA5-4881-A092-0F7ED3B79CA3Q50114279-DE7077EF-F5AC-4EAF-9955-8717C9DB8EFAQ51095426-A9E9F76A-FA6B-46CF-9D6E-CD23D64F93CDQ52340912-80AF4886-C0B8-405B-AB73-0B89C4C8710EQ52593713-B55997BE-123A-499B-BC79-17E72E4B8D03Q57138049-4E4EDB55-F14A-493A-993C-2F62A2A528DE
P2860
Multifunctional compounds: smart molecules for multifactorial diseases.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Multifunctional compounds: smart molecules for multifactorial diseases.
@en
type
label
Multifunctional compounds: smart molecules for multifactorial diseases.
@en
prefLabel
Multifunctional compounds: smart molecules for multifactorial diseases.
@en
P1476
Multifunctional compounds: smart molecules for multifactorial diseases.
@en
P2093
Om Silakari
Yogita Bansal
P356
10.1016/J.EJMECH.2014.01.060
P577
2014-01-31T00:00:00Z