The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis.
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Cancer metastasis: enactment of the script for human reproductive drama.Progesterone induces the growth and infiltration of human astrocytoma cells implanted in the cerebral cortex of the rat.Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex.The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila.The Role of Mifepristone in Meningiomas Management: A Systematic Review of the LiteratureAspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil.Pharmacoproteomic analysis reveals that metapristone (RU486 metabolite) intervenes E-cadherin and vimentin to realize cancer metastasis chemopreventionThe paradigm-shifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives.A General Method for Nucleophilic Aromatic Substitution of Aryl Fluorides and Chlorides with Dimethylamine using Hydroxide-Assisted Decomposition of N,N-Dimethylforamide.Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone.Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486).Mifepristone/RU486 acts in Drosophila melanogaster females to counteract the life span-shortening and pro-inflammatory effects of male Sex Peptide.Genomic and Nongenomic Effects of Mifepristone at the Cardiovascular Level: A Review.The Architecture and Function of Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles Loaded with Mifepristone: Repurposing Abortifacient for Cancer Metastatic Chemoprevention.Mifepristone inhibits ovarian cancer metastasis by intervening in SDF-1/CXCR4 chemokine axisUse of In Vitro Morphogenesis of Mouse Embryoid Bodies to Assess Developmental Toxicity of Therapeutic Drugs Contraindicated in Pregnancy.A structural perspective on nuclear receptors as targets of environmental compounds.Metapristone (RU486 metabolite) suppresses NSCLC by targeting EGFR-mediated PI3K/AKT pathway.Abortifacient metapristone (RU486 derivative) interrupts CXCL12/CXCR4 axis for ovarian metastatic chemoprevention.Thirty-day rat toxicity study reveals reversible liver toxicity of mifepristone (RU486) and metapristone.Synthesis of metapristone through an efficient N-demethylation of mifepristone
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P2860
The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
The unique pharmacological cha ...... preventing cancer metastasis.
@en
type
label
The unique pharmacological cha ...... preventing cancer metastasis.
@en
prefLabel
The unique pharmacological cha ...... preventing cancer metastasis.
@en
P2093
P2860
P356
P1476
The unique pharmacological cha ...... o preventing cancer metastasis
@en
P2093
Jianzhong Chen
Jichuang Wang
Jingwei Shao
Zhenhua Liu
P2860
P304
P356
10.1002/MED.21311
P577
2014-03-01T00:00:00Z