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Pathogenic mechanisms in centronuclear myopathiesSplicing Regulators and Their Roles in Cancer Biology and TherapyStructural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domainBIN1 membrane curvature sensing and generation show autoinhibition regulated by downstream ligands and PI(4,5)P2.Dynamins and BAR Proteins-Safeguards against Cancer.N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.Cardiac T-Tubule Microanatomy and Function.Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ationX-linked myotubular myopathy in Rottweiler dogs is caused by a missense mutation in Exon 11 of the MTM1 genePlasma Membrane Repair: A Central Process for Maintaining Cellular Homeostasis.BIN1 regulates dynamic t-tubule membrane.Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tractsGenetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.Ca²⁺ microdomains organized by junctophilinsMethylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition.Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology.Bin1 directly remodels actin dynamics through its BAR domain.A TMEM16F point mutation causes an absence of canine platelet TMEM16F and ineffective activation and death-induced phospholipid scrambling.Post-Myocardial Infarction T-tubules Form Enlarged Branched Structures With Dysregulation of Junctophilin-2 and Bridging Integrator 1 (BIN-1).Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer's Disease.Alzheimer's Disease: From Genetic Variants to the Distinct Pathological Mechanisms.Amphiphysin (BIN1) negatively regulates dynamin 2 for normal muscle maturation.Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain.BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.Alternative Splicing as a Target for Cancer Treatment.BIN1 reverses PD-L1-mediated immune escape by inactivating the c-MYC and EGFR/MAPK signaling pathways in non-small cell lung cancer.Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Amphiphysin 2 (BIN1) in physiology and diseases.
@en
type
label
Amphiphysin 2 (BIN1) in physiology and diseases.
@en
prefLabel
Amphiphysin 2 (BIN1) in physiology and diseases.
@en
P2093
P2860
P1476
Amphiphysin 2 (BIN1) in physiology and diseases.
@en
P2093
Belinda S Cowling
Ivana Prokic
Jocelyn Laporte
P2860
P2888
P304
P356
10.1007/S00109-014-1138-1
P577
2014-03-05T00:00:00Z
P5875
P6179
1020106781