Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
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Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future researchInside-out neuropharmacology of nicotinic drugsLynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum.Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.Structurally distinct ligands rescue biogenesis defects of the KATP channel complex via a converging mechanism.Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function miceChronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris).Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.The nicotine metabolite, cotinine, alters the assembly and trafficking of a subset of nicotinic acetylcholine receptors.A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α SubunitChronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency.The safety dance: biophysics of membrane protein folding and misfolding in a cellular contextOxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors.Proteins and chemical chaperones involved in neuronal nicotinic receptor expression and function: an update.Insights into nicotinic receptor signaling in nicotine addiction: Implications for prevention and treatment.Cholinergic activity and levodopa-induced dyskinesia: a multitracer molecular imaging study.TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors.Functional Consequences of CHRNA7 Copy-Number Alterations in Induced Pluripotent Stem Cells and Neural Progenitor Cells.Ketamine inside neurons?Organelle-specific single-molecule imaging of α4β2 nicotinic receptors reveals the effect of nicotine on receptor assembly and cell-surface trafficking.Highly Diastereo- and Enantioselective Michael Addition of Nitroalkanes to 2-Enoyl-Pyridine N-Oxides Catalyzed by Scandium(III)/Copper(II) Complexes.Nicotinic Acetylcholine Receptors as Targets for Tobacco Cessation Therapeutics: Cutting-Edge Methodologies to Understand Receptor Assembly and Trafficking.
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P2860
Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
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type
label
Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
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prefLabel
Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
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P2860
P921
P1476
Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease
@en
P2093
Christopher I Richards
Rahul Srinivasan
P2860
P356
10.1016/J.PHRS.2014.02.005
P577
2014-03-01T00:00:00Z