Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
about
Functions of PARylation in DNA Damage Repair PathwaysROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic StrategiesPoly (ADP-ribose) in the pathogenesis of Parkinson's diseaseSex differences in mitochondrial (dys)function: Implications for neuroprotectionEssential versus accessory aspects of cell death: recommendations of the NCCD 2015.A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathwayRegulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis.Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytesThe fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice.Molecular features of the cytotoxicity of an NHE inhibitor: Evidence of mitochondrial alterations, ROS overproduction and DNA damage.Chemical signaling between gut microbiota and host chromatin: What is your gut really saying?Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei.The Different Effects of Atorvastatin and Pravastatin on Cell Death and PARP Activity in Pancreatic NIT-1 Cells.Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degenerationAIF-independent parthanatos in the pathogenesis of dry age-related macular degeneration.The rise and fall of poly(ADP-ribose): An enzymatic perspective.DNA Damage, DNA Repair, Aging, and NeurodegenerationCell Death Mechanisms in Tumoral and Non-Tumoral Human Cell Lines Triggered by Photodynamic Treatments: Apoptosis, Necrosis and Parthanatos.Efficacy of poly (ADP-ribose) polymerase inhibitor olaparib against head and neck cancer cells: Predictions of drug sensitivity based on PAR-p53-NF-κB interactions.Mitochondrial poly(ADP-ribose) polymerase: The Wizard of Oz at work.Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity.Effect of new berberine derivatives on colon cancer cells.Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.The clinically used poly(ADP-ribose) polymerase (PARP) inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third-degree burn injury.Ischemia/Reperfusion.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegenerationMesenchymal stem cells protect neurons against hypoxic-ischemic injury via inhibiting parthanatos, necroptosis, and apoptosis, but not autophagy.Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34.What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses.ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage.Cell Death in the Developing Brain after Hypoxia-IschemiaHYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway.PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD PatientsMitochondrial pharmacology: energy, injury and beyond.Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expression.PARP-1/PAR Activity in Cultured Human Lens Epithelial Cells Exposed to Two Levels of UVB Light.
P2860
Q26744796-80DDAE2F-B454-49BA-A49E-B8A60DA6D7F2Q26747496-7831D064-774C-45C0-BD5E-2C8C1FA2BBCAQ27005667-B7A3DDAC-2392-4994-8201-ED604F1A981DQ28386911-24FEA95B-9B36-4ABB-AAF0-0DC9C315CEEBQ30408769-A92F7435-4697-4697-A043-EC094A547766Q30830656-DF68D9D3-AF7D-42FF-BD84-34F3239F6857Q30830820-4B5118E0-7AFF-476D-BBEA-94ECF3CA560CQ33849064-F45C4AFE-DF45-4023-84FA-A3F20157623CQ33851480-C3F012ED-213B-4DB2-980E-2B958A6E098CQ33925831-D10BB01C-56B9-4FDF-8196-0AFBE8E0BBA1Q34129753-2EFFF313-CCDD-43A7-B1B6-D89AB605BD2BQ35662607-E676A1C5-CC2B-4E93-B103-CDEC463BD038Q36183468-2C2DE4DC-0DFD-4CAD-86BC-A848A674C53DQ36340557-CD38F7CE-F7EF-4808-BC8D-2604A5F4A8BAQ36725115-17CD9EF7-2594-4A15-B116-021CA20ECC6CQ37492634-6AFF2FD2-7D66-46BB-8939-209DF7F61270Q37526029-514F0E9E-ABAF-4252-A405-C0E3BA2C2FC7Q37744863-A846CF33-A6D9-4FD7-A50C-9AFB5EC1AC09Q38473760-D77FBE63-B81A-48BB-BF12-BA4395B60B97Q38589212-08C9656E-B129-4EF4-8D33-DDE3884320E3Q38720024-0DFA1406-612C-4481-A91A-0F32A182AE8BQ38740969-FBCB84EB-FE2A-4CCC-B120-2CE5A3EB1E77Q38768778-E0CD2372-514B-4E5B-932B-FE7935A90A6CQ38780076-B86C0FA4-5F5D-4A55-974C-E92BA6C8CFF8Q38837692-B192A966-7070-491A-847C-8028F11634BBQ38954348-56FD5F83-BBD7-423D-AECE-56FDA11A617AQ38986446-ABF9B48D-5FA2-46F9-9228-744EF9A979D5Q39109413-DD9D05A6-DACE-4DEA-A1E8-13F1AFC2B7DCQ39214221-7BA8C539-DB3F-406D-B217-679F8B529799Q39357662-4EC4BF13-7554-41E8-9D85-DDD1DFF02EDDQ39864426-889C9151-825D-44E1-BB50-9B6C54C01737Q41058708-4E57E6A8-DC92-4CBF-8B74-00AC2555E2E7Q41319392-46B629A4-C38B-47EE-A10C-6BAFF5FB0499Q41335643-BBF79089-AF47-41D4-A80B-4C0AEF2008E3Q41526704-3A4719DB-352A-4081-A92B-B3CF11A25E12Q42021947-A480C969-55AE-4B55-B27C-D7AFD377C884Q42373348-F51F659C-CAB9-4515-A72D-EC2329FD305FQ42374835-7B7AF90E-05FE-4347-9B9F-D6519DA378B3Q42768698-E5104A51-DF56-41E6-8AB9-1CCFDC03C787Q46328761-6588F4B8-25F0-4AD0-9A95-51818A42DB56
P2860
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
@en
type
label
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
@en
prefLabel
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
@en
P2860
P356
P1476
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.
@en
P2093
Amos A Fatokun
P2860
P304
P356
10.1111/BPH.12416
P407
P577
2014-04-01T00:00:00Z