Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer's Disease.
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Monoaminergic and Histaminergic Strategies and Treatments in Brain DiseasesOxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Multitarget-directed tricyclic pyridazinones as G protein-coupled receptor ligands and cholinesterase inhibitors.Multi-target pharmacology: possibilities and limitations of the "skeleton key approach" from a medicinal chemist perspective.Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease.AChE Inhibition-based Multi-target-directed Ligands, a Novel Pharmacological Approach for the Symptomatic and Disease-modifying Therapy of Alzheimer's Disease.New approaches in the design and development of cannabinoid receptor ligands: multifunctional and bivalent compounds.Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration.Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease.Antibody-Based Drugs and Approaches Against Amyloid-β Species for Alzheimer's Disease Immunotherapy.Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer's Disease Therapy.Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.Optimized-SopungSunkiwon, a Herbal Formula, Attenuates Aβ Oligomer-Induced Neurotoxicity in Alzheimer's Disease Models.Antioxidant and Cholinesterase Inhibitory Activities of Ethyl Acetate Extract of Terminalia chebula: Cell-free In vitro and In silico Studies.Advances toward multifunctional cholinesterase and β-amyloid aggregation inhibitors.Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.Synthesis and anticholinesterase activity of new substituted benzo[d]oxazole-based derivatives.Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages.Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors.Computer-Aided Multi-Target Management of Emergent Alzheimer's Disease.Multitarget effects of Korean Red Ginseng in animal model of Parkinson's disease: antiapoptosis, antioxidant, antiinflammation, and maintenance of blood-brain barrier integrity.Xanthone and Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer Agents
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P2860
Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer's Disease.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Multi-Target Directed Drugs: A ...... atment of Alzheimer's Disease.
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type
label
Multi-Target Directed Drugs: A ...... atment of Alzheimer's Disease.
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prefLabel
Multi-Target Directed Drugs: A ...... atment of Alzheimer's Disease.
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P2860
P1476
Multi-Target Directed Drugs: A ...... atment of Alzheimer's Disease.
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P2093
Claudio Viegas
Kris Simone Tranches Dias
P2860
P304
P356
10.2174/1570159X1203140511153200
P577
2014-05-01T00:00:00Z