5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects.
about
An ancient riboswitch class in bacteria regulates purine biosynthesis and one-carbon metabolismSerine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional RegulatorsDisruption of Nucleotide Homeostasis by the Antiproliferative Drug 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside Monophosphate (AICAR).New synthetic AICAR derivatives with enhanced AMPK and ACC activation.New biomarkers for early diagnosis of Lesch-Nyhan disease revealed by metabolic analysis on a large cohort of patients.Synthesis of new acadesine (AICA-riboside) analogues having acyclic D-ribityl or 4-hydroxybutyl chains in place of the ribose.Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans.AMPK in skeletal muscle function and metabolism.Untargeted metabolomics confirms and extends the understanding of the impact of aminoimidazole carboxamide ribotide (AICAR) in the metabolic network of Salmonella enterica.AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2.Evolutionary convergence in the biosyntheses of the imidazole moieties of histidine and purines.A facile synthesis of 5'-fluoro-5'-deoxyacadesine (5'-F-AICAR): a novel non-phosphorylable AICAR analogue.
P2860
Q28610747-68BDB252-5EAD-4AC4-8F36-C87A5292F185Q30316637-D11D70F0-CF6A-458E-A415-6B0895E3AA29Q35908579-887EF01D-0530-4D5E-9AAE-D7F913DED33CQ36092969-1FE66D28-F99D-4789-A21A-7032323F558FQ38829598-E1853755-AE0F-4B3A-B1A0-398325B79533Q41810483-E9C5AE9B-5A25-4F63-A885-FAF7CD6EA6EBQ42278323-153E7234-AD21-4C0E-9BCA-0E6019B0BB0CQ46177112-B406EF12-E3FA-4013-A4DD-F51237C4E5C6Q47781006-A73BB508-4760-43DC-B4CB-3580E6BC161BQ49391863-34C0E242-7BA6-422D-A494-E63B520BDA6CQ54112169-443DCE88-1E9D-430C-BD0C-D0ED8BA6126DQ55256769-786BB037-4381-448F-B2DC-584CBEB3FB52Q59133291-C72F1ADB-5F03-40A0-8305-F35E52D4B9FB
P2860
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
5-Aminoimidazole-4-carboxamide ...... mediate with Multiple Effects.
@en
type
label
5-Aminoimidazole-4-carboxamide ...... mediate with Multiple Effects.
@en
prefLabel
5-Aminoimidazole-4-carboxamide ...... mediate with Multiple Effects.
@en
P2860
P356
P1433
P1476
5-Aminoimidazole-4-carboxamide ...... mediate with Multiple Effects.
@en
P2093
Benoît Pinson
Bertrand Daignan-Fornier
P2860
P304
P356
10.3390/METABO2020292
P577
2012-03-23T00:00:00Z