about
Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV PersistenceThe Combination of the R263K and T66I Resistance Substitutions in HIV-1 Integrase Is Incompatible with High-Level Viral Replication and the Development of High-Level Drug Resistance.Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.Combination of the R263K and M184I/V resistance substitutions against dolutegravir and lamivudine decreases HIV replicative capacity.HIV-1 integrase inhibition: looking at cofactor interactions.
P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Integrase Strand Transfer Inhibitors in HIV Therapy.
@en
type
label
Integrase Strand Transfer Inhibitors in HIV Therapy.
@en
prefLabel
Integrase Strand Transfer Inhibitors in HIV Therapy.
@en
P2860
P1476
Integrase Strand Transfer Inhibitors in HIV Therapy
@en
P2093
Mark A Wainberg
P2860
P2888
P356
10.1007/S40121-013-0020-8
P577
2013-11-19T00:00:00Z
P5875
P6179
1034084791