Strategic approaches to optimizing peptide ADME properties
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A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of FerroptosisProspects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial PeptidesNox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule InhibitorsPeptides and Peptide Analogs to Inhibit Protein-Protein Interactions.TANGO-Inspired Design of Anti-Amyloid Cyclic Peptides.Original insights on thrombospondin-1-related antireceptor strategies in cancer.A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses.Strategies of GnRH synthetic analogues determination in doping control: in vitro and in vivo metabolism data; evaluation of LH and steroid profile parameters fluctuations as suitable biomarkers.THPdb: Database of FDA-approved peptide and protein therapeuticsShort peptides interfering with signaling pathways as new therapeutic tools for cancer treatment.The Potential Therapeutic Application of Peptides and Peptidomimetics in Cardiovascular Disease.An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides.Lipopeptides as therapeutics: applications and in vivo quantitative analysis.Update and trends on pharmacokinetic studies in patients with impaired renal function: practical insight into application of the FDA and EMA guidelines.In vivo characterisation of a therapeutically relevant self-assembling 18 F-labelled β-sheet forming peptide and its hydrogel using positron emission tomography.Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products.Peptide Developability at the Discovery-to-Development Interface--Current State and Future Opportunities.Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's diseaseSoftware-aided approach to investigate peptide structure and metabolic susceptibility of amide bonds in peptide drugs based on high resolution mass spectrometry.Degradation Paradigm of the Gut Hormone, Pancreatic Polypeptide, by Hepatic and Renal Peptidases.2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines 'Scientific'? (Part 1 - LCMS: small molecules, peptides and small molecule biomarkers).Peptibodies: An elegant solution for a long-standing problem.Peptide Lipidation - A Synthetic Strategy to Afford Peptide Based Therapeutics.Synthesis and Assessment of Peptide Gd-DOTA Conjugates Targeting Extradomain B Fibronectin for Magnetic Resonance Molecular Imaging of Prostate Cancer.Molecular engineering solutions for therapeutic peptide delivery.Characterization and in vivo efficacy of a heptapeptide ODT formulation for the treatment of neurogenic bladder dysfunction.N-tert-butyloxycarbonyl-Phe-Leu-Phe-Leu-Phe (BOC2) inhibits the angiogenic activity of heparin-binding growth factors.Population pharmacokinetics of exendin-(9-39) and clinical dose selection in patients with congenital hyperinsulinism.Progress in the formulation and delivery of somatostatin analogs for acromegaly.Peptide Mediated Brain Delivery of Nano- and Submicroparticles: a Synergistic Approach.Total Synthesis of Scytonemide A Employing Weinreb AM Solid-Phase Resin.Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis.Specific Amyloid Binding of Polybasic Peptides In Vivo Is Retained by β-Sheet Conformers but Lost in the Disrupted Coil and All D-Amino Acid Variants.The Potential for Connexin Hemichannels to Drive Breast Cancer Progression through Regulation of the Inflammatory Response.Discovery of a novel potent peptide agonist to adiponectin receptor 1.Synthetic fermentation of β-peptide macrocycles by thiadiazole-forming ring-closing reactions.Lipophilicity prediction of peptides and peptide derivatives by consensus machine learningThermally Reduced Graphene Oxide Nanohybrids of Chiral Functional Naphthalenediimides for Prostate Cancer Cells BioimagingNuclear factor-kappa B: Glucocorticoid-induced leucine zipper interface analogs suppress pathology in an Alzheimer's disease model
P2860
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P2860
Strategic approaches to optimizing peptide ADME properties
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Strategic approaches to optimizing peptide ADME properties
@en
type
label
Strategic approaches to optimizing peptide ADME properties
@en
prefLabel
Strategic approaches to optimizing peptide ADME properties
@en
P2860
P1433
P1476
Strategic approaches to optimizing peptide ADME properties
@en
P2093
P2860
P2888
P304
P356
10.1208/S12248-014-9687-3
P407
P577
2014-11-04T00:00:00Z
P6179
1005305973