Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. - Wikidata - awgldk - TriplyDB

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.

http://www.wikidata.org/entity/Q38272367

about

Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation.Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration.The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth.SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.Functional screen identifies regulators of murine hematopoietic stem cell repopulation The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.A rationale to target the SWI/SNF complex for cancer therapy.Vulnerabilities of mutant SWI/SNF complexes in cancer.Chromatin remodeler mutations in human cancers: epigenetic implications.Endoplasmic reticulum stress, genome damage, and cancer.BRG1 regulation by miR-155 in human leukemia and lymphoma cell lines.The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia SWI/SNF proteins as targets in cancer therapy.A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia.A New Way Forward in Cancer Drug Discovery: Inhibiting the SWI/SNF Chromatin Remodelling Complex.A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia.High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis.The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer.

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Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.

http://www.wikidata.org/entity/Q38272367

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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Essential role of BRG, the ATP ...... exes, in leukemia maintenance.

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Essential role of BRG, the ATP ...... exes, in leukemia maintenance.

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Essential role of BRG, the ATP ...... lexes, in leukemia maintenance

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Brian Wilhelm

http://www.w3.org/2001/XMLSchema#string

Camille Simon

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Gerald R Crabtree

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Guy Sauvageau

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Josée Hébert

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Julie A Lessard

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Manuel Buscarlet

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Pierre Thibault

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Veneta Krasteva

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P2860

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.

Histone variants--ancient wrap artists of the epigenome

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

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