Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy.
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Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a DerivativeMitochondrial expression and activity of P-glycoprotein under oxidative stress in outer blood-retinal barrierQuantification of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein inducer/activator, in biological samples: method development and validation.Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans.A novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment.A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function.Effect of MDR1 gene polymorphisms on mortality in paraquat intoxicated patients.The Role of Eukaryotic and Prokaryotic ABC Transporter Family in Failure of Chemotherapy.Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms.Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.Integrated proteomic and N-glycoproteomic analyses of doxorubicin sensitive and resistant ovarian cancer cells reveal glycoprotein alteration in protein abundance and glycosylation.Potential drug interactions associated with glycyrrhizin and glycyrrhetinic acid.Application of Evolutionary Principles to Cancer TherapyDownregulation of hepatic multi-drug resistance protein 1 (MDR1) after copper exposure.MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner.The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.Flavonoids as modulators of metabolic enzymes and drug transporters.The long chain α-tocopherol metabolite α-13'-COOH and γ-tocotrienol induce P-glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180.In vitro and in silico analysis of the vascular effects of asymmetrical N,N-bis(alkanol)amine aryl esters, novel multidrug resistance-reverting agents.Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Dahuang Zhechong Pill Combined with Doxorubicin Induces Cell Death through Regulating Energy Metabolism in Human Hepatocellular Carcinoma Cells.Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer.Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination.LncRNA plasmacytoma variant translocation 1 is an oncogene in bladder urothelial carcinoma.P-glycoprotein multidrug transporter in inflammatory bowel diseases: More questions than answers.Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia.Anti-cancer Activity of Natural and Synthetic Capsaicin Analogs.Metformin enhances doxorubicin sensitivity via inhibition of doxorubicin efflux in P-gp-overexpressing MCF-7 cells.Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling.Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins?Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers.Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models.Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals.Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport.Anthocyanidins but not anthocyanins inhibit P-glycoprotein-mediated calcein extrusion - possible implication for orally administered drugs.Knockdown of long non-coding RNA KCNQ1OT1 depressed chemoresistance to paclitaxel in lung adenocarcinoma.
P2860
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P2860
Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Modulation of P-glycoprotein e ...... ion as a therapeutic strategy.
@en
type
label
Modulation of P-glycoprotein e ...... ion as a therapeutic strategy.
@en
prefLabel
Modulation of P-glycoprotein e ...... ion as a therapeutic strategy.
@en
P50
P1476
Modulation of P-glycoprotein e ...... tion as a therapeutic strategy
@en
P2093
Maria de Lourdes Bastos
P356
10.1016/J.PHARMTHERA.2014.11.013
P50
P577
2014-11-27T00:00:00Z