Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.
about
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactylyOverlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish developmentHes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndromeGata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb DevelopmentMsx1 and Msx2 in limb mesenchyme modulate digit number and identityOn the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cellsCochlear progenitor number is controlled through mesenchymal FGF receptor signalingTgfbeta2 and 3 are coexpressed with their extracellular regulator Ltbp1 in the early limb bud and modulate mesodermal outgrowth and BMP signaling in chicken embryos.Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterningSP8 regulates signaling centers during craniofacial development.The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney developmentPatterning a complex organ: branching morphogenesis and nephron segmentation in kidney developmentThe cortical hem regulates the size and patterning of neocortexTbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.Modulation of fibroblast growth factor signaling is essential for mammary epithelial morphogenesis.HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis.Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasisETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.ETS-related transcription factors ETV4 and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cellsFGF23 promotes prostate cancer progression.A misplaced lncRNA causes brachydactyly in humans.FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung BranchingEpithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney developmentFGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development.Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish.Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital developmentFeedback control of the EGFR signaling gradient: superposition of domain-splitting events in Drosophila oogenesis.An increased duplication of ZRS region that caused more than one supernumerary digits preaxial polydactyly in a large Chinese family.How the embryo makes a limb: determination, polarity and identity.Prickle1 stunts limb growth through alteration of cell polarity and gene expressionCell signaling pathways in the adrenal cortex: Links to stem/progenitor biology and neoplasia.Pea3 Transcription Factors, Etv4 and Etv5, Are Required for Proper Hippocampal Dendrite Development and Plasticity.Anterior-posterior differences in HoxD chromatin topology in limb development.Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus.Spatiotemporal regulation of GLI target genes in the mammalian limb bud.Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryoIdentification of spontaneous mutations within the long-range limb-specific Sonic hedgehog enhancer (ZRS) that alter Sonic hedgehog expression in the chicken limb mutants oligozeugodactyly and silkie breed.Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis
P2860
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P2860
Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Fgf-dependent Etv4/5 activity ...... growth of the vertebrate limb.
@en
type
label
Fgf-dependent Etv4/5 activity ...... growth of the vertebrate limb.
@en
prefLabel
Fgf-dependent Etv4/5 activity ...... growth of the vertebrate limb.
@en
P2093
P2860
P1433
P1476
Fgf-dependent Etv4/5 activity ...... growth of the vertebrate limb.
@en
P2093
Andrew P McMahon
Clifford J Tabin
Junhao Mao
P2860
P304
P356
10.1016/J.DEVCEL.2009.02.005
P407
P577
2009-04-01T00:00:00Z