Structures of mGluRs shed light on the challenges of drug development of allosteric modulators.
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GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators.Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus biasLeveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.Organization and functions of mGlu and GABAB receptor complexes.Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives.Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective.Methods for Virtual Screening of GPCR Targets: Approaches and Challenges.
P2860
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P2860
Structures of mGluRs shed light on the challenges of drug development of allosteric modulators.
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2014 nî lūn-bûn
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2014年学术文章
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name
Structures of mGluRs shed ligh ...... ment of allosteric modulators.
@en
type
label
Structures of mGluRs shed ligh ...... ment of allosteric modulators.
@en
prefLabel
Structures of mGluRs shed ligh ...... ment of allosteric modulators.
@en
P2093
P1476
Structures of mGluRs shed ligh ...... ment of allosteric modulators.
@en
P2093
Andrew S Doré
Fiona H Marshall
John A Christopher
Kirstie A Bennett
P356
10.1016/J.COPH.2014.09.022
P577
2014-10-17T00:00:00Z