Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole - Wikidata - awgldk - TriplyDB

Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole

Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole

http://www.wikidata.org/entity/Q38280950

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Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole Intravitreal itraconazole inhibits laser-induced choroidal neovascularization in rats.The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.Repurposing the Clinically Efficacious Antifungal Agent Itraconazole as an Anticancer Chemotherapeutic.A chiral enantioseparation generic strategy for anti-Alzheimer and antifungal drugs by short end injection capillary electrophoresis using an experimental design approach.Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling.Highly enantioselective hydrogenation of 1-alkylvinyl benzoates: a simple, nonenzymatic access to chiral 2-alkanols.

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Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole

http://www.wikidata.org/entity/Q38280950

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2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

2010年學術文章

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2010年學術文章

@zh-hant

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Impact of Absolute Stereochemi ...... gal Activities of Itraconazole

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ACS Medicinal Chemistry Letters

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Impact of Absolute Stereochemi ...... gal Activities of Itraconazole

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Benjamin A Nacev

http://www.w3.org/2001/XMLSchema#string

Jun O Liu

http://www.w3.org/2001/XMLSchema#string

Shridhar Bhat

http://www.w3.org/2001/XMLSchema#string

Wei Shi

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P2860

Cholesterol trafficking is required for mTOR activation in endothelial cells

Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

Stereoisomers of ketoconazole: preparation and biological activity

Inhibition of angiogenesis by the antifungal drug itraconazole.

Biochemical basis for the activity and selectivity of oral antifungal drugs.

Stereochemical aspects of itraconazole metabolism in vitro and in vivo.

Structure-activity relationship of quinoline derivatives as potent and selective alpha(2C)-adrenoceptor antagonists.

Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole.

Antimycotic azoles. 7. Synthesis and antifungal properties of a series of novel triazol-3-ones.

Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.

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155-159

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scholarly article

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10.1021/ML1000068

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4

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1

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2010-01-01T00:00:00Z

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51618767

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21892383

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