The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.
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Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNAScurfin (FOXP3) acts as a repressor of transcription and regulates T cell activationMechanisms regulating expression of the tumor necrosis factor-related light gene. Role of calcium-signaling pathway in the transcriptional controlGlucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching.NF-kappaB is involved in the regulation of CD154 (CD40 ligand) expression in primary human T cellsMultiple cytokines sharing the common receptor gamma chain can induce CD154/CD40 ligand expression by human CD4+ T lymphocytes via a cyclosporin A-resistant pathwayIn vivo post-transcriptional regulation of CD154 in mouse CD4+ T cells.X-linked immunodeficiency with hyper-IgM (XHIM).IL-15 prolongs CD154 expression on human CD4 T cells via STAT5 binding to the CD154 transcriptional promoter.Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis.Early growth response-1 is required for CD154 transcription.Major peptide autoepitopes for nucleosome-centered T and B cell interaction in human and murine lupus.Impaired NFAT and NFκB activation are involved in suppression of CD40 ligand expression by Δ(9)-tetrahydrocannabinol in human CD4(+) T cells.The role of CD40 ligand in systemic lupus erythematosus.Deregulated expression of CD40 ligand in HTLV-I infection: distinct mechanisms of downregulation in HTLV-I-transformed cell lines and ATL patients.Immunotherapy targeting the CD40/CD154 costimulatory pathway for treatment of autoimmune disease.Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a.Tumor necrosis factor-α blockade treatment decreased CD154 (CD40-ligand) expression in rheumatoid arthritis.NFATc1/αA: The other Face of NFAT Factors in Lymphocytes.A tissue-specific, activation-inducible, lentiviral vector regulated by human CD40L proximal promoter sequences.Delineation of a novel pathway that regulates CD154 (CD40 ligand) expressionNF-kappaB is involved in regulation of CD40 ligand expression on Mycobacterium bovis bacillus Calmette-Guérin-activated human T cells.T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1.Functional analysis of a tripartite stability element within the CD40 ligand 3' untranslated region.Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival.Calcium-dependent activation of interleukin-21 gene expression in T cells.A T cell-specific enhancer of the human CD40 ligand gene.The impact of Nucleofection® on the activation state of primary human CD4 T cellsRegulation of the murine Nfatc1 gene by NFATc2.Low levels of NF-κB/p65 mark anergic CD4+ T cells and correlate with disease severity in sarcoidosis.Endothelial cell and cAMP regulation of T-cell CD40 ligand: relevance of calcium/calmodulin-dependent kinase IV signalling.Costimulatory blockade prevents early rejection, promotes lymphocyte apoptosis, and inhibits the upregulation of intragraft interleukin-6 in an orthotopic liver transplant model in the rat.Role of the cyclosporin-sensitive transcription factor NFAT1 in the allergic response.Intronic enhancer activity of the eosinophil-derived neurotoxin (RNS2) and eosinophil cationic protein (RNS3) genes is mediated by an NFAT-1 consensus binding sequence.A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter.Hyper-immunoglobulin M syndrome caused by a mutation in the promotor for CD40L.
P2860
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P2860
The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
The human gp39 promoter. Two d ...... to transcriptional activation.
@en
type
label
The human gp39 promoter. Two d ...... to transcriptional activation.
@en
prefLabel
The human gp39 promoter. Two d ...... to transcriptional activation.
@en
P2093
P356
P1476
The human gp39 promoter. Two d ...... to transcriptional activation
@en
P2093
P304
29624-29627
P356
10.1074/JBC.270.50.29624
P407
P577
1995-12-01T00:00:00Z