Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
about
Integrated physiology and systems biology of PPARαTranscriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell functionOrphan nuclear receptors and the regulation of nutrient metabolism: understanding obesityt-10, c-12 CLA dietary supplementation inhibits atherosclerotic lesion development despite adverse cardiovascular and hepatic metabolic marker profilesRole of n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity-Induced Metabolic Syndrome in Animal Models and HumansRecent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKsNrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genesInvestigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormoneRegulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.Regulation of islet beta-cell pyruvate metabolism: interactions of prolactin, glucose, and dexamethasone.Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases.Regulation of hepatic fat and glucose oxidation in rats with lipid-induced hepatic insulin resistance.Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytesPPAR-alpha effects on the heart and other vascular tissues.Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements.Genetic manipulations of PPARs: effects on obesity and metabolic disease.Olive Leaf Extract Elevates Hepatic PPAR α mRNA Expression and Improves Serum Lipid Profiles in Ovariectomized Rats.Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic AcidNordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways.PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in miceGlycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.PPARs: diverse regulators in energy metabolism and metabolic diseases.Role of PPARα in Hepatic Carbohydrate Metabolism.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?Pre-natal undernutrition and post-natal overnutrition are associated with permanent changes in hepatic metabolism markers and fatty acid composition in sheep.Genomic profiles and predictors of early allograft dysfunction after human liver transplantation.Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivationLeptin deficiency contributes to the pathogenesis of alcoholic fatty liver disease in mice.A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver.S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism.Peroxisome proliferator-activated receptor alpha target genes.Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-activated receptor alpha deficiency.MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa.Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin.Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).PDK4: A factor in fatness?
P2860
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P2860
Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Peroxisome-proliferator-activa ...... ism by fatty acids and insulin
@en
type
label
Peroxisome-proliferator-activa ...... ism by fatty acids and insulin
@en
prefLabel
Peroxisome-proliferator-activa ...... ism by fatty acids and insulin
@en
P2093
P2860
P356
P1433
P1476
Peroxisome-proliferator-activa ...... ism by fatty acids and insulin
@en
P2093
Brian L Knight
Geoffrey F Gibbons
Karen Bulmer
Mark J Holness
Mary C Sugden
P2860
P304
P356
10.1042/BJ20011699
P407
P577
2002-06-01T00:00:00Z