Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1.
about
Separate roles of structured and unstructured regions of Y-family DNA polymerasesA rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adductsVersatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine AdductsStructure of the Human Rev1–DNA–dNTP Ternary ComplexStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESBasis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA PolymerasesStructure and Functional Analysis of the BRCT Domain of Translesion Synthesis DNA Polymerase Rev1Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota.Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.Variations on a theme: eukaryotic Y-family DNA polymerasesKinetic basis of nucleotide selection employed by a protein template-dependent DNA polymeraseBiochemical analysis of six genetic variants of error-prone human DNA polymerase ι involved in translesion DNA synthesis.The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.Translesion synthesis across abasic lesions by human B-family and Y-family DNA polymerases α, δ, η, ι, κ, and REV1Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein.Synthetic nucleotides as probes of DNA polymerase specificity.Effects of N(2)-alkylguanine, O(6)-alkylguanine, and abasic lesions on DNA binding and bypass synthesis by the euryarchaeal B-family DNA polymerase vent (exo(-))Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis.Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases.Liquid Chromatography-Tandem Mass Spectrometry for the Quantification of Tobacco-Specific Nitrosamine-Induced DNA Adducts in Mammalian Cells.DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens.Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι.Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage.Incorporation of nucleoside probes opposite O⁶-methylguanine by Sulfolobus solfataricus DNA polymerase Dpo4: importance of hydrogen bonding.In vitro bypass of the major malondialdehyde- and base propenal-derived DNA adduct by human Y-family DNA polymerases κ, ι, and Rev1.Replication bypass of N2-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι.Novel view on the mechanism of water-assisted proton transfer in the DNA bases: bulk water hydration.
P2860
Q24630493-EBCF5547-94E8-4597-890A-EE91FC5C8449Q27025418-7CC95F9F-1BB8-4191-A435-0B2F957609D5Q27653071-5B568F36-039A-436F-A1C0-5C09B53445D6Q27655583-1226528C-4635-4320-82AB-2535F979E707Q27656089-DD273B29-B71C-4487-8B96-3E776215E14DQ27671647-CC42D36C-7ED2-4618-BB0C-745B640B5E22Q27675497-2016EAAE-984B-49EB-A7A4-F01DC5CDCD34Q33568383-6F023195-AEDB-422C-B5EC-91DCCE423DA5Q33623563-DEBB534C-2F3E-42D2-B253-FF45CAD7AD6BQ33756190-D7041698-3D8C-4CA2-89DF-A9D534B66255Q34009370-D1BAFA74-AE7E-40EA-ADFE-7DC3231BCC63Q34372430-229F8241-6F75-42AD-A48D-419BCFD54518Q34477514-BF54A86A-2F9A-47B1-BEF6-1370C05056CFQ34479547-965B3F79-5BDC-4B46-8E0E-64BEE92D3645Q35400041-A0D9306D-6127-401D-B455-AB3E0E231E78Q36040168-575AB422-EA9F-4FB8-B2A6-F80861B465D3Q36930807-B06A5FFF-39C9-4362-8B87-568BD405432BQ37371343-C47226DF-2B24-414D-896C-78920CD6ECD1Q37424345-A160DEE4-A427-41A2-90CA-91E81011E3D4Q38166683-E9391AA0-B2BF-47D1-BD7F-9B3F288408B1Q38203300-5154662E-F6B3-4CD0-A264-7E97CD44B03BQ38651032-52587826-56A5-44A7-87AF-A02B6D85AFA7Q40003876-B6FEF3CD-6D35-49AE-B1BB-D679F1AE00E7Q41549472-3042B9D0-977F-49D2-99BD-A02D41B86EE8Q41843974-59C49608-3253-4CEE-B01B-0D02E80A1A44Q41881334-DD722B12-7400-4829-A561-6FAB6AC703C4Q41966583-3C0A397B-D371-4255-9101-8CBD8D820927Q43074239-0AA04123-52F7-4790-A339-2DF3CDE11FB1Q46019449-84AC6AFB-3CDC-4BDE-93A3-ACE75B34CA0D
P2860
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Kinetic analysis of translesio ...... by human DNA polymerase REV1.
@en
type
label
Kinetic analysis of translesio ...... by human DNA polymerase REV1.
@en
prefLabel
Kinetic analysis of translesio ...... by human DNA polymerase REV1.
@en
P2860
P356
P1476
Kinetic analysis of translesio ...... by human DNA polymerase REV1.
@en
P2093
F Peter Guengerich
Jeong-Yun Choi
P2860
P304
23645-23655
P356
10.1074/JBC.M801686200
P407
P577
2008-06-30T00:00:00Z