6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding si
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GTP cyclohydrolase I utilizes metal-free GTP as its substrateTetrahydrobiopterin biosynthesis, regeneration and functionsStructure of a 6-pyruvoyltetrahydropterin synthase homolog fromStreptomyces coelicolorBiochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold SuperfamilySerine 19 of human 6-pyruvoyltetrahydropterin synthase is phosphorylated by cGMP protein kinase IIIdentification of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency in four Italian familiesChromosomal localization, genomic structure and characterization of the human gene and a retropseudogene for 6-pyruvoyltetrahydropterin synthaseSpectroscopic, steady-state kinetic, and mechanistic characterization of the radical SAM enzyme QueE, which catalyzes a complex cyclization reaction in the biosynthesis of 7-deazapurinesThe 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase.Functional promiscuity of the COG0720 familyPurification, crystallization and preliminary crystallographic analysis of archaeal 6-pyruvoyl tetrahydrobiopterin synthase homologue PH0634 from Pyrococcus horikoshii OT3The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment.Novel mutation affecting the pterin-binding site of PTS gene and review of PTS mutations in Thai patients with 6-pyruvoyltetrahydropterin synthase deficiency.Biosynthesis of drosopterins, the red eye pigments of Drosophila melanogaster.Reconstitution of a metabolic pathway with triple-cistronic IRES-containing retroviral vectors for correction of tetrahydrobiopterin deficiency.An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites.High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analoguePlasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?DHNTP is dephosphorylated by PTPS to PTHPStructural and Functional Consequences of Mutations in 6-Pyruvoyltetrahydropterin Synthase Causing Hyperphenylalaninemia in Humans
P2860
Q24304340-859D6BA1-D9FF-4D39-BD2E-BEC98BBCDA02Q24531994-D2D43F9A-9595-4558-A60D-703D947EE420Q27652567-98C3576E-399F-447B-8F3A-7768946088A3Q27684533-BE686491-2AF1-46DD-B957-C54ABC90D233Q28146022-C0C107B7-5650-4493-B2EA-93ED9870FAD5Q28243574-B35089D3-D3FA-4A79-8AD0-236FC5901E77Q28292289-A93CD04B-9D0F-46B6-88E5-5BEEA796185DQ28488943-0471AA1C-3770-4407-8ED4-3361CA2BFB63Q28587841-A736F4EE-5792-4ACD-8775-CAC84FF03AD4Q34949346-4B4E5790-3B19-45A7-9496-877C7A1F65F8Q35685500-63C36433-A512-45C5-8962-EF136C07E195Q36580344-D9B54F58-218A-4E51-8596-4C8DE845A5D9Q36862775-3E4C4189-4D8D-452C-99D1-72F5ABEA2037Q37615166-DB497EBB-8FC0-4F95-9C5D-ACC0823281E9Q38084230-6B16D839-C1B6-4488-AFFD-A33F4B8BDF22Q40886880-9F239134-9A4C-4A3F-A488-ADCC59D2D409Q41940305-C38EC8BC-DAF2-4739-B4FF-DDD4DB62938AQ42015563-1DF9FADB-BBDB-4651-944A-59FB09D41097Q42061540-F1FC27E2-792B-4ABE-BF8B-96EA39E631C9Q50294460-6E292A11-DCF1-44FE-A600-64D9506EF53AQ56700952-1B30D380-48A1-4112-87B6-EAAE8101BDEC
P2860
6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding si
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
6-Pyruvoyl tetrahydropterin sy ...... zation of the metal binding si
@en
type
label
6-Pyruvoyl tetrahydropterin sy ...... zation of the metal binding si
@en
prefLabel
6-Pyruvoyl tetrahydropterin sy ...... zation of the metal binding si
@en
P2093
P356
P1476
6-Pyruvoyl tetrahydropterin sy ...... zation of the metal binding si
@en
P2093
Bürgisser DM
Heizmann CW
P304
P356
10.1006/JMBI.1995.0558
P407
P577
1995-10-01T00:00:00Z