Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites.
about
FoxA2 involvement in suppression of protein C, an outcome predictor in experimental sepsisGenetic susceptibility to inflammatory injury and various adverse outcomesThe transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression.Transcriptional regulation of the gene coding for human protein C.The phenotypic and genetic assessment of protein C deficiency.Familial thrombotic risk based on the genetic background of Protein C Deficiency in a Portuguese Study.Unique distance- and DNA-turn-dependent interactions in the human protein C gene promoter confer submaximal transcriptional activity.The molecular basis for genetic polymorphism of human deoxyribonuclease II (DNase II): a single nucleotide substitution in the promoter region of human DNase II changes the promoter activity.Molecular characterization of wilson disease in the Sardinian population--evidence of a founder effect.CRISPR-Cas9 HDR system enhances AQP1 gene expression.Type I protein C deficiency caused by disruption of a hepatocyte nuclear factor (HNF)-6/HNF-1 binding site in the human protein C gene promoter.
P2860
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P2860
Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
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1995年學術文章
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name
Two mutations in the promoter ...... on of two HNF-3 binding sites.
@en
type
label
Two mutations in the promoter ...... on of two HNF-3 binding sites.
@en
prefLabel
Two mutations in the promoter ...... on of two HNF-3 binding sites.
@en
P2093
P2860
P356
P1476
Two mutations in the promoter ...... on of two HNF-3 binding sites.
@en
P2093
Bertina RM
Greengard JS
Griffin JH
Reitsma PH
P2860
P304
24216-24221
P356
10.1074/JBC.270.41.24216
P407
P577
1995-10-01T00:00:00Z