Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.
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The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitationsBoth 5' and 3' flanks regulate Zebrafish brain-derived neurotrophic factor gene expressionEmergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterialsGinger stimulates hematopoiesis via Bmp pathway in zebrafishA gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis.Early endocardial morphogenesis requires Scl/Tal1Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic InsightsZebrafish as a model for leukemia and other hematopoietic disordersOceans of opportunity: exploring vertebrate hematopoiesis in zebrafishAn ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.Discovering chemical modifiers of oncogene-regulated hematopoietic differentiationZebrafish in hematology: sushi or science?CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis.VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines.Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish.Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish.Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survivalA non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish modelsDynamic niches in the origination and differentiation of haematopoietic stem cells.Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish.Expression analysis of Runx3 and other Runx family members during Xenopus developmentScl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells.The zebrafish as a model for cancer.Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved.Signalling pathways that control vertebrate haematopoietic stem cell specification.Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila modelRegulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a.Hematopoietic stem cell fate is established by the Notch-Runx pathway.Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia.Runx3 knockouts and stomach cancerA manual small molecule screen approaching high-throughput using zebrafish embryos.Zebrafish as a Model for the Study of Human Myeloid Malignanciesklf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes.Danio rerio: Small Fish Making a Big Splash in LeukemiaExpression of the pair-rule gene homologs runt, Pax3/7, even-skipped-1 and even-skipped-2 during larval and juvenile development of the polychaete annelid Capitella teleta does not support a role in segmentation.RAD21 mutations cause a human cohesinopathy
P2860
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P2860
Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Runx1 is required for zebrafis ...... for studies of leukemogenesis.
@en
type
label
Runx1 is required for zebrafis ...... for studies of leukemogenesis.
@en
prefLabel
Runx1 is required for zebrafis ...... for studies of leukemogenesis.
@en
P2093
P1433
P1476
Runx1 is required for zebrafis ...... for studies of leukemogenesis
@en
P2093
Andrea M Baas
John H Postlethwait
Julia A Horsfield
Kathryn E Crosier
Maggie L Kalev-Zylinska
Maria R Vitas
Maria Vega C Flores
Philip S Crosier
P304
P407
P577
2002-04-01T00:00:00Z