Point mutations in awdKpn which revert the prune/Killer of prune lethal interaction affect conserved residues that are involved in nucleoside diphosphate kinase substrate binding and catalysis.
about
A structural mechanism for dimeric to tetrameric oligomer conversion inHalomonassp. nucleoside diphosphate kinaseNucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallographyThe nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritancePRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairmentDrosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development.Germline transformation using a prune cDNA rescues prune/killer of prune lethality and the prune eye color phenotype in Drosophila.AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis.Loss-of-function mutations in a glutathione S-transferase suppress the prune-Killer of prune lethal interaction.The proliferation of Drosophila in cancer research: a system for the functional characterization of tumor suppressors and oncogenes.Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix.Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity.Assessment of normal and mutant human presenilin function in Caenorhabditis elegans.Developmental function of Nm23/awd: a mediator of endocytosis.The Drosophila metastasis suppressor gene Nm23 homolog, awd, regulates epithelial integrity during oogenesis.Nucleotide affinity for a stable phosphorylated intermediate of nucleoside diphosphate kinase.Nucleoside diphosphate kinases (NDPKs) in animal development.PRUNE1: a disease-causing gene for secondary microcephaly.A single Gly114Arg mutation stabilizes the hexameric subunit assembly and changes the substrate specificity of halo-archaeal nucleoside diphosphate kinase.Histidine kinases and the missing phosphoproteome from prokaryotes to eukaryotes.Structure of Nm23-H1 under oxidative conditions.The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities.
P2860
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P2860
Point mutations in awdKpn which revert the prune/Killer of prune lethal interaction affect conserved residues that are involved in nucleoside diphosphate kinase substrate binding and catalysis.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
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1995年學術文章
@zh-hant
name
Point mutations in awdKpn whic ...... bstrate binding and catalysis.
@en
type
label
Point mutations in awdKpn whic ...... bstrate binding and catalysis.
@en
prefLabel
Point mutations in awdKpn whic ...... bstrate binding and catalysis.
@en
P2093
P2860
P356
P1476
Point mutations in awdKpn whic ...... bstrate binding and catalysis.
@en
P2093
P2860
P304
23021-23030
P356
10.1074/JBC.270.39.23021
P407
P577
1995-09-01T00:00:00Z