Recognition of base J in duplex DNA by J-binding protein.
about
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in LeishmaniaFormation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1Trypanosome telomeres are protected by a homologue of mammalian TRF2.Identification of the glucosyltransferase that converts hydroxymethyluracil to base J in the trypanosomatid genome.Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.JBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNAJBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomesA novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.JBP2, a SWI2/SNF2-like protein, regulates de novo telomeric DNA glycosylation in bloodstream form Trypanosoma brucei.The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads.
P2860
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P2860
Recognition of base J in duplex DNA by J-binding protein.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Recognition of base J in duplex DNA by J-binding protein.
@en
type
label
Recognition of base J in duplex DNA by J-binding protein.
@en
prefLabel
Recognition of base J in duplex DNA by J-binding protein.
@en
P2093
P2860
P356
P1476
Recognition of base J in duplex DNA by J-binding protein.
@en
P2093
Jacques H van Boom
Nico Meeuwenoord
Piet Borst
Robert Sabatini
P2860
P304
P356
10.1074/JBC.M109000200
P407
P577
2001-11-07T00:00:00Z