Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats.
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Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feedingAge-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin SensitivityRole of leptin resistance in the development of obesity in older patientsCentral nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposityFood for thought: the role of appetitive peptides in age-related cognitive declineMkks-null mice have a phenotype resembling Bardet-Biedl syndromeCentral overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasisTargeted leptin receptor blockade: role of ventral tegmental area and nucleus of the solitary tract leptin receptors in body weight homeostasis.Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area.Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity.Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in ratsActivation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity.A role for central nervous system PPAR-γ in the regulation of energy balancePreventing leptin resistance by blocking angiotensin II AT1 receptors in diet-induced obese rats.The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese ratsATP-Sensitive Potassium Channel-Deficient Mice Show Hyperphagia but Are Resistant to Obesity.A polymorphism in the 5'-untranslated region of the porcine cholecystokinin type a receptor gene affects feed intake and growth.Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity.Peptides and their potential role in the treatment of diabetes and obesity.Effects of Gengnianchun on learning and memory ability, neurotransmitter, cytokines, and leptin in ovariectomized rats.The anorectic effect of CNTF does not require action in leptin-responsive neurons.Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease.Intracerebroventricular injection of metformin induces anorexia in rats.Ghrelin, adipokines, metabolic factors in relation with weight status in school-children and results of a 1-year lifestyle intervention program.Leptin overexpression in VTA trans-activates the hypothalamus whereas prolonged leptin action in either region cross-desensitizes.Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice.Obesity, leptin, and Alzheimer's diseaseLeptin-induced increase in body fat content of rats.Sarcopenic obesity and endocrinal adaptation with ageOnset of leptin resistance shows temporal differences related to dose or pulsed treatmentProlonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity.Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life.JAK-STAT and feeding.Leptin resistance: a prediposing factor for diet-induced obesityLeptin signaling in brain: A link between nutrition and cognition?The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo.Serum leptin level and cognition in the elderly: Findings from the Health ABC Study.Chronic blockade of angiotensin AT₁ receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats.Influence of age on leptin induced skeletal muscle signalling.Neonatal leptin treatment programmes leptin hypothalamic resistance and intermediary metabolic parameters in adult rats.
P2860
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P2860
Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Hypothalamic leptin resistance ...... ansduction in aged obese rats.
@en
type
label
Hypothalamic leptin resistance ...... ansduction in aged obese rats.
@en
prefLabel
Hypothalamic leptin resistance ...... ansduction in aged obese rats.
@en
P2093
P1433
P1476
Hypothalamic leptin resistance ...... ansduction in aged obese rats.
@en
P2093
P304
P356
10.1016/S0306-4522(01)00142-7
P407
P577
2001-01-01T00:00:00Z