A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. - Wikidata - awgldk - TriplyDB

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.

http://www.wikidata.org/entity/Q38299437

about

Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2 Targeting androgen receptor in estrogen receptor-negative breast cancer Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression Androgen regulation of the prostatic tumour suppressor NKX3.1 is mediated by its 3' untranslated region A transcriptional repressor co-regulatory network governing androgen response in prostate cancers RhoA as a mediator of clinically relevant androgen action in prostate cancer cells Pioneer transcription factors: establishing competence for gene expression FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6 Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases The convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancer Interplay between genomic alterations and androgen receptor signaling during prostate cancer development and progression Lipid metabolism in prostate cancer A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical research Emerging data on androgen receptor splice variants in prostate cancer A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer cells The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.The mutational landscape of lethal castration-resistant prostate cancer Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells.CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation C/EBPalpha redirects androgen receptor signaling through a unique bimodal interaction Target analysis by integration of transcriptome and ChIP-seq data with BETA.Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries Microarray Analysis of the Major Depressive Disorder mRNA Profile Data Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor.Genome-wide mechanisms of nuclear receptor action.Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes.Biased, non-equivalent gene-proximal and -distal binding motifs of orphan nuclear receptor TR4 in primary human erythroid cells

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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.

http://www.wikidata.org/entity/Q38299437

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A hierarchical network of tran ...... endent prostate cancer growth.

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Arul M Chinnaiyan

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Erika Krasnickas Keeton

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Jason S Carroll

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Olli A Jänne

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Qianben Wang

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Wei Li

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X Shirley Liu

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P2860

Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase

The program of androgen-responsive genes in neoplastic prostate epithelium.

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

The nuclear receptor superfamily: the second decade

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Oct-1 preferentially interacts with androgen receptor in a DNA-dependent manner that facilitates recruitment of SRC-1

Combinatorial control of gene expression by nuclear receptors and coregulators

ONCOMINE: a cancer microarray database and integrated data-mining platform

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