Antisense depletion of beta-subunits modulates the biophysical and pharmacological properties of neuronal calcium channels.
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Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell lineA short history of voltage-gated calcium channelsPain perception in mice lacking the beta3 subunit of voltage-activated calcium channelsAntisense oligonucleotides against rat brain alpha1E DNA and its atrial homologue decrease T-type calcium current in atrial myocytesThe ß subunit of voltage-gated Ca2+ channelsDominant-negative suppression of Cav2.1 currents by alpha(1)2.1 truncations requires the conserved interaction domain for beta subunits.Ablation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memoryImmunohistochemical localization of voltage-gated calcium channels in substantia nigra dopamine neurons.Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.Molecular and functional diversity of voltage-gated calcium channels.Impaired renal calcium absorption in mice lacking calcium channel beta 3 subunits.Mechanisms of modulation of voltage-dependent calcium channels by G proteins.Age-dependent contribution of P/Q- and R-type Ca2+ channels to neuromuscular transmission in lethargic mice.Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits.Membrane-localized β-subunits alter the PIP2 regulation of high-voltage activated Ca2+ channels.Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neuronsVascular calcium channels and high blood pressure: pathophysiology and therapeutic implications.Unique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation.Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channelTrafficking and stability of voltage-gated calcium channels.Structure and function of the β subunit of voltage-gated Ca²⁺ channels.Dissection of the calcium channel domains responsible for modulation of neuronal voltage-dependent calcium channels by G proteins.Two PEST-like motifs regulate Ca2+/calpain-mediated cleavage of the CaVbeta3 subunit and provide important determinants for neuronal Ca2+ channel activity.Acidic motif responsible for plasma membrane association of the voltage-dependent calcium channel beta1b subunit.Facilitation of rabbit alpha1B calcium channels: involvement of endogenous Gbetagamma subunits.Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture.Use of a purified and functional recombinant calcium-channel beta4 subunit in surface-plasmon resonance studies.Calcineurin involvement in the regulation of high-threshold Ca2+ channels in NG108-15 (rodent neuroblastoma x glioma hybrid) cells.The effect of overexpression of auxiliary Ca2+ channel subunits on native Ca2+ channel currents in undifferentiated mammalian NG108-15 cells.Voltage-gated calcium channels: their discovery, function and importance as drug targetsInhibition of rat ventricularI K1 with antisense oligonucleotides targeted to Kir2.1 mRNA
P2860
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P2860
Antisense depletion of beta-subunits modulates the biophysical and pharmacological properties of neuronal calcium channels.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Antisense depletion of beta-su ...... of neuronal calcium channels.
@en
type
label
Antisense depletion of beta-su ...... of neuronal calcium channels.
@en
prefLabel
Antisense depletion of beta-su ...... of neuronal calcium channels.
@en
P2093
P1476
Antisense depletion of beta-su ...... of neuronal calcium channels.
@en
P2093
A C Dolphin
E M Fitzgerald
K Brickley
N S Berrow
V Campbell
P304
P356
10.1113/JPHYSIOL.1995.SP020534
P407
P478
482 ( Pt 3)
P577
1995-02-01T00:00:00Z