Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
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HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoterMechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cellsDivergent regulation of the growth-promoting gene IEX-1 by the p53 tumor suppressor and Sp1Sp1 and p73 activate PUMA following serum starvationExamination of the expanding pathways for the regulation of p21 expression and activity.A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 geneThe p53 circuit boardIdentification of functional p53-binding motifs in the mouse wig-1 promoterp53 coordinates base excision repair to prevent genomic instabilityIdentification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised ClusteringZBTB2, a novel master regulator of the p53 pathway.p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription.Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73.Mist1 regulates pancreatic acinar cell proliferation through p21 CIP1/WAF1Role of promyelocytic leukemia zinc finger (PLZF) in cell proliferation and cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) gene repression.Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genesATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter.Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathwayGATA-1 directly regulates p21 gene expression during erythroid differentiationA synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.Retinal transcriptome profiling at transcription start sites: a cap analysis of gene expression early after axonal injury.p53 Represses transcription of RING finger LIM domain-binding protein RLIM through Sp1The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutationsmiR-22 represses cancer progression by inducing cellular senescenceFormation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elementsThe tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.P21Waf1 control of epithelial cell cycle and cell fate.Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.Wild-type p53 controls cell motility and invasion by dual regulation of MET expressionTranscriptional regulation of the cyclin-dependent kinase inhibitor 1A (p21) gene by NFI in proliferating human cellsEffect of apoptosis on gastric adenocarcinoma cell line SGC-7901 induced by cis-9, trans-11-conjugated linoleic acid.Regulation of the cyclin-dependent kinase inhibitor 1A gene (CDKN1A) by the repressor BOZF1 through inhibition of p53 acetylation and transcription factor Sp1 binding.Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis.Transcription factor Sp3 represses expression of p21CIP¹ via inhibition of productive elongation by RNA polymerase II.The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa).5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.The cyclin A1-CDK2 complex regulates DNA double-strand break repair.The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.Stressing mitosis to death.
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P2860
Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Sp1 plays a critical role in t ...... p53 tumor suppressor protein.
@en
type
label
Sp1 plays a critical role in t ...... p53 tumor suppressor protein.
@en
prefLabel
Sp1 plays a critical role in t ...... p53 tumor suppressor protein.
@en
P2093
P2860
P356
P1476
Sp1 plays a critical role in t ...... p53 tumor suppressor protein.
@en
P2093
Kardassis D
Koutsodontis G
Moustakas A
Papakosta P
P2860
P304
29116-29125
P356
10.1074/JBC.M104130200
P407
P577
2001-05-30T00:00:00Z