A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.

A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.

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http://www.wikidata.org/entity/Q38300613
Targeting cancer using cholesterol conjugatesFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNAThe G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cellsA small molecule inhibitor of Pot1 binding to telomeric DNA.G4 motifs correlate with promoter-proximal transcriptional pausing in human genes.A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region.Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compoundG4LDB: a database for discovering and studying G-quadruplex ligands.Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.A hitchhiker's guide to G-quadruplex ligands.Stabilization of G-quadruplex DNA, inhibition of telomerase activity and live cell imaging studies of chiral ruthenium(II) complexes.Aminoglycoside binding to Oxytricha nova telomeric DNA.Targeting telomeric G-quadruplexes with the ruthenium(II) complexes [Ru(bpy)(2)(ptpn)](2+) and [Ru(phen)(2)(ptpn)](2+).Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity.PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays.Trigeminal star-like platinum complexes induce cancer cell senescence through quadruplex-mediated telomere dysfunction
P2860

A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.

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http://www.wikidata.org/entity/Q38300613
description
2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
@zh-hk
2007年論文
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2007年論文
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2007年论文
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2007年论文
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2007年论文
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name
A new steroid derivative stabi ...... ncapping in human tumor cells.
@en
type
label
A new steroid derivative stabi ...... ncapping in human tumor cells.
@en
prefLabel
A new steroid derivative stabi ...... ncapping in human tumor cells.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
A new steroid derivative stabi ...... uncapping in human tumor cells
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698