The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
about
MicroRNAs and their target gene networks in breast cancerLoss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive CancersLZTFL1 suppresses gastric cancer cell migration and invasion through regulating nuclear translocation of β-cateninFunctional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophiesZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1On how CCN6 suppresses breast cancer growth and invasionThe ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transitionCancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expressionA reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cellsLet-7 and miR-200 microRNAs: guardians against pluripotency and cancer progressionDoes GATA3 act in tissue-specific pathways? A meta-analysis-based approachCell polarity signaling in the plasticity of cancer cell invasivenessMicroRNA Regulation of Epithelial to Mesenchymal TransitionThe miR-200 Family: Versatile Players in Epithelial Ovarian CancerImplications of the Hybrid Epithelial/Mesenchymal Phenotype in MetastasisWounds that will not heal: pervasive cellular reprogramming in cancerEmerging role of cell polarity proteins in breast cancer progression and metastasisTissue-based identification of stem cells and epithelial-to-mesenchymal transition in breast cancerInteractions between E-cadherin and microRNA deregulation in head and neck cancers: the potential interplayEpithelial cell polarity determinant CRB3 in cancer developmentThe miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identityZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistanceThe emerging molecular machinery and therapeutic targets of metastasisDuctal barriers in mammary epitheliummiR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal TransitionThe microRNA-200 family: small molecules with novel roles in cancer development, progression and therapyMicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agentsTGF-β-induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loopsmiR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expressionResveratrol inhibits cisplatin-induced epithelial-to-mesenchymal transition in ovarian cancer cell linesDe-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signalingTGF-beta-induced epithelial to mesenchymal transitionZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cellsIdentifying cancer-related microRNAs based on gene expression data.Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries.Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulationComplete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
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The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The transcription factor ZEB1 ...... lators of epithelial polarity.
@en
type
label
The transcription factor ZEB1 ...... lators of epithelial polarity.
@en
prefLabel
The transcription factor ZEB1 ...... lators of epithelial polarity.
@en
P2093
P2860
P50
P356
P1433
P1476
The transcription factor ZEB1 ...... lators of epithelial polarity.
@en
P2093
A Wernitznig
L Descovich
N Schweifer
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210508
P407
P577
2007-05-07T00:00:00Z
P5875
P6179
1031449424