The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules.
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Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallographyThe structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replicationBinding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2′,5′)adenosineConserved water molecules in a large family of microbial ribonucleasesProductive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2′,5′)guanosineMapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitorsConformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 Å resolutionReversible substrate-induced domain motions in ribonuclease AA nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical studyHigh-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitorsA new crystal form of bovine pancreatic RNase A in complex with 2′-deoxyguanosine-5′-monophosphateRibonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and their Evolutionary ImplicationsInfluence of naturally-occurring 5â ²-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic studyFunctional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase ACrystal structure of Onconase at 1.1 Å resolution - insights into substrate binding and collective motionCrystal structures of murine angiogenin-2 and -3 - probing ‘structure - function’ relationships amongst angiogenin homologuesCrystal structures of the copper and nickel complexes of RNase A: metal-induced interprotein interactions and identification of a novel copper binding motifInteraction of human pancreatic ribonuclease with human ribonuclease inhibitor. Generation of inhibitor-resistant cytotoxic variantsImidazole C-2 hydrogen/deuterium exchange reaction at histidine for probing protein structure and function with matrix-assisted laser desorption ionization mass spectrometry.Atomic hydration potentials using a Monte Carlo Reference State (MCRS) for protein solvation modeling.Two crystal structures of the leupeptin-trypsin complex.Structural and functional importance of local and global conformational fluctuations in the RNase A superfamily.RNase-stable RNA: conformational parameters of the nucleic acid backbone for binding to RNase T1.His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.Ternary borate-nucleoside complex stabilization by ribonuclease A demonstrates phosphate mimicry.Molecular dynamics simulation of bovine pancreatic ribonuclease A-CpA and transition state-like complexesAnalysis of the mechanism of the Serratia nuclease using site-directed mutagenesisCharacterization of disulfide bonds by planned digestion and tandem mass spectrometry.Recognition of ribonuclease A by 3'-5'-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis.Interpretation of pH-activity profiles for acid-base catalysis from molecular simulationsConserved water molecules contribute to the extensive network of interactions at the active site of protein kinase AThe mechanism of rate-limiting motions in enzyme function.Using NMR spectroscopy to elucidate the role of molecular motions in enzyme functionThree-dimensional structure of the complexes of ribonuclease A with 2',5'-CpA and 3',5'-d(CpA) in aqueous solution, as obtained by NMR and restrained molecular dynamics.The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangementRibozyme catalysis revisited: is water involved?Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2'-O-transphosphorylation.Inhibitor design for ribonuclease A: the binding of two 5'-phosphate uridine analogues.Packing at the protein-water interfaceModeling of angiogenin - 3-NMP complex.
P2860
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P2860
The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The structures of RNase A comp ...... and conserved water molecules.
@en
type
label
The structures of RNase A comp ...... and conserved water molecules.
@en
prefLabel
The structures of RNase A comp ...... and conserved water molecules.
@en
P2093
P2860
P356
P1433
P1476
The structures of RNase A comp ...... and conserved water molecules.
@en
P2093
P2860
P304
P356
10.1002/PRO.5560031217
P577
1994-12-01T00:00:00Z