Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues.
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Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathwayMolecular and phenotypic aspects of CHD7 mutation in CHARGE syndromeDefects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndromeMutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndromeChromodomain helicase DNA-binding proteins in stem cells and human developmental diseasesThe role of CHD7 and the newly identified WDR11 gene in patients with idiopathic hypogonadotropic hypogonadism and Kallmann syndromeRegulation of chromatin structure in the cardiovascular systemOtitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 geneCHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairmentMutation update on the CHD7 gene involved in CHARGE syndromeA critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular developmentGreat vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in miceSox2 cooperates with Chd7 to regulate genes that are mutated in human syndromesNELF knockout is associated with impaired pubertal development and subfertility.Epigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.Reproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome.Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome.The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear.Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient miceHarnessing molecular motors for nanoscale pulldown in live cells.Chromatin remodeling in development and disease: focus on CHD7.CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expressionCHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesisThe chromatin remodeling protein CHD7, mutated in CHARGE syndrome, is necessary for proper craniofacial and tracheal developmentCHD7 mutations and CHARGE syndrome in semicircular canal dysplasia.Inappropriate p53 activation during development induces features of CHARGE syndrome.Study of smell and reproductive organs in a mouse model for CHARGE syndrome.Epigenetic Developmental Disorders: CHARGE syndrome, a case studyArchitects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesIdentification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.Epigenetic regulation in neural crest development.Chromatin remodelling during development.Chromatin remodeling in cardiovascular development and physiology.Chromodomain proteins in development: lessons from CHARGE syndrome.Xenopus: An emerging model for studying congenital heart disease.Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome.Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders.Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier.
P2860
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P2860
Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Loss of Chd7 function in gene- ...... n multiple developing tissues.
@en
type
label
Loss of Chd7 function in gene- ...... n multiple developing tissues.
@en
prefLabel
Loss of Chd7 function in gene- ...... n multiple developing tissues.
@en
P2093
P1433
P1476
Loss of Chd7 function in gene- ...... in multiple developing tissues
@en
P2093
Donna M Martin
Elizabeth A Hurd
Heather K Poucher
Marsha N Blauwkamp
Meredith E Adams
Yehoash Raphael
P2860
P2888
P304
P356
10.1007/S00335-006-0107-6
P577
2007-02-28T00:00:00Z