about
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assaysTotal synthesis of taxolTotal synthesis of brevetoxin ACharacterization of potent fusion inhibitors of influenza virusDiversity oriented synthesis and branching reaction pathway to generate natural product-like compounds.Synthesis of catechins via thiourea/AuCl(3)-catalyzed cycloalkylation of aryl epoxides.Converse conformational control of smoothened activity by structurally related small molecules.Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling.Development of new stereodiverse diaminocyclitols as inhibitors of influenza virus neuraminidase.Discovery and SAR study of piperidine-based derivatives as novel influenza virus inhibitors.Concise synthesis of isoquinoline via the Ugi and Heck reactions.Strategic innovation in the total synthesis of complex natural products using gold catalysis.Efficient total synthesis of bioactive natural products: a personal record.Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis.A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001.Rapid biomimetic total synthesis of (±)-rossinone B.Total synthesis of (±) maoecrystal V.Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode.Gold-catalyzed rearrangement of allylic oxonium ylides: efficient synthesis of highly functionalized dihydrofuran-3-ones.Synthesis of 4-substituted coumarins via the palladium-catalyzed cross-couplings of 4-tosylcoumarins with terminal acetylenes and organozinc reagents.Highly regioselective syntheses of substituted triphenylenes from 1,2,4-trisubstituted arenes via a co-catalyzed intermolecular alkyne cyclotrimerization.Palladium-catalyzed cross-coupling reactions of 4-tosyl-2(5H)-furanone with boronic acids: a facile and efficient route to generate 4-substituted 2(5H)-furanones.Total synthesis of methyl protodioscin: a potent agent with antitumor activity.Reverse regioselectivity in the palladium(II) thiourea catalyzed intermolecular Pauson-Khand reaction.Asymmetric, protecting-group-free total synthesis of (+)-caribenol A.Copper-free sonogashira coupling reaction with PdCl2 in water under aerobic conditions.Stereoselective total syntheses of (-)-flueggine A and (+)-virosaine B.Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin.Direct imidation to construct 1H-benzo[d]imidazole through Pd(II)-catalyzed C-H activation promoted by thiourea.One-pot syntheses of isoquinolin-3-ones and benzo-1,4-diazepin-2,5-diones utilizing Ugi-4CR post-transformation strategy.Identification of a highly efficient alkylated pincer thioimido-palladium(II) complex as the active catalyst in Negishi coupling.Pincer thioamide and pincer thioimide palladium complexes catalyze highly efficient Negishi coupling of primary and secondary alkyl zinc reagents at room temperature.Development of an expedient intramolecular Pauson-Khand reaction approach to stereoselectively construct the trans-decalin with a C1 quaternary chiral center.Asymmetric total synthesis of (-)-lingzhiol via a Rh-catalysed [3+2] cycloaddition.A concise and diversity-oriented approach to the synthesis of SAG derivatives.Enantioselective Total Synthesis of (-)-Pavidolide B.Asymmetric Total Synthesis of Lancifodilactone G Acetate.A rhodium-catalyzed tandem reaction of N-sulfonyl triazoles with indoles: access to indole-substituted indanones.Reductant-directed formation of PS-PAMAM-supported gold nanoparticles for use as highly active and recyclable catalysts for the aerobic oxidation of alcohols and the homocoupling of phenylboronic acids.
P50
Q21092150-CCDC3515-75DB-4236-BF4D-6F2630DB0BD8Q28237249-9B514DAB-3275-4BCA-9272-F7BD6B02500FQ28265878-F94C1859-0609-4EA1-8362-5A1F8BB13EC4Q28544971-83F62AB5-D779-4E9C-8D75-8CA513B89439Q31007743-AF87E12B-FD43-43D5-8CCD-2044E9FE6C00Q33337180-80F5AE98-5F1E-4C37-8ED4-AB19D94087C2Q33430191-1D6B57AC-1658-45EF-824A-8960761A3CEFQ33510167-798D1BA0-BC6B-4EB6-9103-D00453C618F1Q33517703-57F87974-B051-4FEC-854F-79E8DAD63E29Q34253013-F9223564-006F-4617-8986-8EBE080A359BQ34343486-E42F27E4-8F8E-4D48-972C-25CCB535522CQ38183271-B657AAEF-2540-48ED-89FC-726540DF3630Q38232014-9A859EC4-30B4-4905-9823-9EA5322B04C8Q38579612-53F6F2EC-CBC9-4024-8BB2-FFF2021DED79Q39121242-9B0B0B91-9C35-4151-B595-4B9E0EA3862FQ39297951-7A3EF226-EFB5-4637-8C18-9465F2AC0743Q42827103-BDDED84D-3D75-4F2F-88C2-B6215D866C26Q42836822-8B351DA1-3CFC-4A8F-8EA8-E848169EBB5DQ43210448-F369955B-EFC6-4A1E-A83C-A7C1A6C071EAQ43436631-61812DFE-2ADA-4EB8-95DC-1F1EF1D7A1E0Q43604301-E65FB1EE-8468-4F0E-AFEB-12EFF8FF4B44Q43883506-FF904CD9-F59C-4E58-BBCA-FE7768CBBA0EQ44280356-774E5E71-5086-4C0D-89B8-8FE23C337EF2Q44416096-AE2ABDAC-B5DE-4400-9DFF-44FA34B572D4Q44613156-AC27EB08-B32D-41AA-AE66-92EF0590CF26Q44996166-3C1372A9-6799-4721-A9A7-0C38DAB91809Q45206075-118FFF53-522B-4042-B4D1-6AE74BCE6661Q45342316-EC628445-5664-4E4C-B65E-EAC26DE20386Q45753376-0B3B331B-570D-46D3-98A4-1076FB590C94Q45955395-31F1D175-8ABA-4683-AD35-7099B305A86BQ46077623-EA5FB511-823F-46A3-9782-3C213EDDB32BQ46087395-4E437EA9-9E12-46FE-89A5-1D46F389DF6AQ46186691-4F3C47D2-B000-4F9C-85AA-AACAF748ACA2Q46437502-5B42D34E-DE65-4310-81F9-8F2D6F4565D5Q46801616-CD136979-C439-4B82-A2D3-CDFD325C6FEFQ47377246-9EFA6D50-3ECA-4BEC-A64C-8099C9B920D3Q47718883-AFDA2CCE-5468-4EC9-A9C6-682004F74914Q48299848-7D81DF47-16F0-4F31-A246-59008693F1CEQ48708327-5B07C014-4129-4D91-B95F-4659D94CB555Q49209269-4E667CE5-648C-40ED-BDBA-DE4B885600B1
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Zhen Yang
@ast
Zhen Yang
@en
Zhen Yang
@es
Zhen Yang
@sl
type
label
Zhen Yang
@ast
Zhen Yang
@en
Zhen Yang
@es
Zhen Yang
@sl
altLabel
zhen yang
@en
prefLabel
Zhen Yang
@ast
Zhen Yang
@en
Zhen Yang
@es
Zhen Yang
@sl
P1053
J-6306-2015
P106
P31
P3829
P496
0000-0001-8036-934X
P569
2000-01-01T00:00:00Z