The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.
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Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesisEpigenetic modifications unlock the milk protein gene loci during mouse mammary gland development and differentiationSignificance of oncogenes and tumor suppressor genes in AML prognosis.Identification and characterization of CCAAT/Enhancer Binding proteindelta (C/EBPdelta) target genes in G0 growth arrested mammary epithelial cellsMulticenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia.Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy.The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer.Treatment of FLT3-ITD-positive acute myeloid leukemia relapsing after allogeneic stem cell transplantation with sorafenibEarly aberrant DNA methylation events in a mouse model of acute myeloid leukemia.Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression.C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expressionMethylation status of DDIT3 gene in chronic myeloid leukemiaCCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cellsCCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.CCAAT/Enhancer Binding Protein-delta (C/EBP-delta) regulates cell growth, migration and differentiationThe tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis.Epigenetic differences in cytogenetically normal versus abnormal acute myeloid leukemia.C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation.The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylatedEvaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells.CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis.Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.Site-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBPδ) CpG island in breast cancer is associated with metastatic relapseIntegrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples.Decitabine Compared with Low-Dose Cytarabine for the Treatment of Older Patients with Newly Diagnosed Acute Myeloid Leukemia: A Pilot Study of Safety, Efficacy, and Cost-Effectiveness.C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric groovesDeficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mousePIASy represses CCAAT/enhancer-binding protein delta (C/EBPdelta) transcriptional activity by sequestering C/EBPdelta to the nuclear periphery.Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.Rad GTPase inhibits cardiac fibrosis through connective tissue growth factorp53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex.Epigenetics in acute myeloid leukemia.The many faces of C/EBPδ and their relevance for inflammation and cancer.MECP2 promotes the growth of gastric cancer cells by suppressing miR-338-mediated antiproliferative effect.Applications of microarray technology to Acute Myelogenous LeukemiaDecitabine in the treatment of acute myeloid leukemia in elderly patients.
P2860
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P2860
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The C/EBPdelta tumor suppresso ...... ion in acute myeloid leukemia.
@en
type
label
The C/EBPdelta tumor suppresso ...... ion in acute myeloid leukemia.
@en
prefLabel
The C/EBPdelta tumor suppresso ...... ion in acute myeloid leukemia.
@en
P2093
P1433
P1476
The C/EBPdelta tumor suppresso ...... ion in acute myeloid leukemia.
@en
P2093
Dirk van den Boom
Hubert Serve
Mathias Ehrich
Nicola Tidow
Shuchi Agrawal
Wolf-Karsten Hofmann
Wolfgang E Berdel
P304
P356
10.1182/BLOOD-2006-08-040147
P407
P577
2007-01-18T00:00:00Z