Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action.
about
The role of peroxidation of mitochondrial membrane phospholipids in pancreatic β -cell failureMitochondrial regulation of β-cell function: maintaining the momentum for insulin releaseUncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen speciesDynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cellsUCP2 protects hypothalamic cells from TNF-alpha-induced damageUnsaturated fatty acids revert diet-induced hypothalamic inflammation in obesityUCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells.Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretionHigh-fat diet induces apoptosis of hypothalamic neuronsVariation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention StudyUnacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice.The regulation and turnover of mitochondrial uncoupling proteins.Inflammation of the hypothalamus leads to defective pancreatic islet function.Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional -866G>A Promoter Variant (rs659366)Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus.Metabolic and pancreatic effects of bone marrow mesenchymal stem cells transplantation in mice fed high-fat diet.Expression of PPARalpha modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice.The role of uncoupling proteins in diabetes mellitusDefective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity.The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction.Uncoupling protein 2 Ala55Val polymorphism is associated with a higher acute insulin response to glucose.Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.RETRACTED: EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice.UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation.Mitochondrial pathophysiology and type 2 diabetes mellitus.Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice.Thyroid hormone-stimulated increases in PGC-1α and UCP2 promote life history-specific endocrine changes and maintain a lipid-based metabolism.Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models.Defective regulation of adipose tissue autophagy in obesity.Transgenerational effects of obesity and malnourishment on diabetes risk in F2 generation.The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.UCP2 -866G/A and Ala55Val, and UCP3 -55C/T polymorphisms in association with type 2 diabetes susceptibility: a meta-analysis study.Effects of renin-angiotensin system blockade on the islet morphology and function in rats with long-term high-fat diet.Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine
P2860
Q26995759-92A4C7CC-2908-4E95-9917-FBCA5C2F585DQ28083598-00F0D3D1-3809-42CB-8022-A9439820B148Q28565465-09CB045B-DDFB-4E76-AF84-EC63CBFCAEACQ28574719-9FA0A353-616C-42E2-9CBF-12A39F91748EQ28575626-09684648-B920-424A-8C62-234E13F7A98BQ28580433-73DFBA3A-6038-46F5-BB63-CEF3F8AEF1D0Q33312956-34167DEF-AF99-47EB-BFE1-0BDAB46A801BQ33391087-F399A3F3-C952-4C6E-BA8C-C47319182CA9Q33425926-FAAE86B0-85D9-4E18-B077-EC95ED65F2CFQ33505454-2CDC2F82-D60D-4DCB-871C-D8CFBD366046Q33644530-FE240C56-DD6F-4CDA-A92A-F5B9D458FED3Q33936374-5787148E-519E-45B5-B2F2-870087A4F708Q34787014-BC609C52-AAF5-46BD-8317-E9E5EB0793ACQ34974646-E7E9D43D-5991-475F-8E90-60005A026654Q35550591-E1821188-D346-493C-BDD4-1CA886B04AC0Q35552255-0D4A5B5E-4985-408B-937A-126C5DC7FF28Q35688480-B88A487E-29FE-4239-8EE6-736FA375CE0CQ36942760-7E2ACD7F-A705-4526-A581-29BA561F18D7Q37062026-6EEABC9D-BCB9-4C37-9974-62CD9FC36BBCQ37242460-6E85BBF8-75EC-4D8A-BC49-83A92BDE8A82Q37246082-D8DD41C3-6BD2-463F-8EBD-3A35F6665803Q37341488-136F6661-590E-4554-BF6F-1E0C552A31EDQ37429236-80B9E8DB-5342-4EE2-9254-83625CC0967AQ37519690-175DCC01-BEE9-4AC5-8B8A-567EFEEA75F1Q37889277-2C4704D6-FC62-4D8E-8431-7E8C98D004A4Q38521312-7FEB37E0-6DF4-4D86-BEFB-A31CE7A4F62CQ38693949-CA7E5AE1-0F53-4062-AD74-F2574A5F3653Q38984636-C1C12B2F-5052-4945-BC64-44F5B1BC33CDQ44982422-C246973D-64F4-430C-95BF-A02476FC9DE8Q46618369-EEB86FB0-326C-4911-B018-A95322B6ED64Q51360789-858BACDB-7C2F-49CB-98D2-E137EB85D1F9Q53086619-2F82B074-457A-4C1C-812D-CF2508987EA4Q53312680-0AA050AD-77D3-4F27-B248-9B6FD1C00334Q58798685-C4838DD5-4DDB-4BC5-BCEF-2CE4CCC3D934
P2860
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Inhibition of UCP2 expression ...... insulin secretion and action.
@en
type
label
Inhibition of UCP2 expression ...... insulin secretion and action.
@en
prefLabel
Inhibition of UCP2 expression ...... insulin secretion and action.
@en
P2093
P356
P1433
P1476
Inhibition of UCP2 expression ...... insulin secretion and action.
@en
P2093
Antonio C Boschero
Cláudio T De Souza
Eduardo Ropelle
Eliana P Araújo
Everardo M Carneiro
José B Carvalheira
José R Pauli
Kleber G Franchini
Luiz F Stoppiglia
Lício A Velloso
P304
P356
10.1096/FJ.06-7148COM
P407
P577
2007-01-05T00:00:00Z