about
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA polymerase IIA SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damageThe multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription terminationRrp6: Integrated roles in nuclear RNA metabolism and transcription terminationFail-safe transcription termination: Because one is never enoughDisengaging polymerase: terminating RNA polymerase II transcription in budding yeastCoupling pre-mRNA processing to transcription on the RNA factory assembly lineThe Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domainStructural insights into cis element recognition of non-polyadenylated RNAs by the Nab3-RRMCooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domaincis -Proline-mediated Ser(P) 5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogueA bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast.Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation.The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathwaySen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repairBudding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination.The Rpb4 subunit of RNA polymerase II contributes to cotranscriptional recruitment of 3' processing factors.A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeastCleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiaeNuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts.Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis.Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control.Polyadenylation linked to transcription termination directs the processing of snoRNA precursors in yeast.Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae.Transcriptome-wide binding sites for components of the Saccharomyces cerevisiae non-poly(A) termination pathway: Nrd1, Nab3, and Sen1.Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear ExosomeRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeThe role of Ctk1 kinase in termination of small non-coding RNAsGenome-wide mapping of yeast RNA polymerase II terminationThe exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathwayBackmasking in the yeast genome: encoding overlapping information for protein-coding and RNA degradationTranscription termination by nuclear RNA polymerasesProgression through the RNA polymerase II CTD cycleA genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3.PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeastA highly conserved gene island of three genes on chromosome 3B of hexaploid wheat: diverse gene function and genomic structure maintained in a tightly linked block.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Distinct pathways for snoRNA and mRNA termination.
@en
type
label
Distinct pathways for snoRNA and mRNA termination.
@en
prefLabel
Distinct pathways for snoRNA and mRNA termination.
@en
P2093
P1433
P1476
Distinct pathways for snoRNA and mRNA termination.
@en
P2093
Alexander Zhelkovsky
Claire Moore
Minkyu Kim
Stephen Buratowski
P304
P356
10.1016/J.MOLCEL.2006.11.011
P577
2006-12-01T00:00:00Z