Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation.
about
Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markersBiology of fibroblasts and myofibroblastsThe myofibroblast: one function, multiple originsPathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2Selective blockade of cytoskeletal actin remodeling reduces experimental choroidal neovascularizationHydrostatic intestinal edema induced signaling pathways: potential role of mechanical forces.New strategy to control cell migration and metastasis regulated by CCN2/CTGF.The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytesMir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness.Calcineurin mediates bladder wall remodeling secondary to partial outlet obstruction.FosB regulates stretch-induced expression of extracellular matrix proteins in smooth muscle.Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 geneMechanical stretch inhibits lipopolysaccharide-induced keratinocyte-derived chemokine and tissue factor expression while increasing procoagulant activity in murine lung epithelial cells.Maintenance of radiation-induced intestinal fibrosis: cellular and molecular featuresCCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress.Mechanical strain activates a program of genes functionally involved in paracrine signaling of angiogenesis.TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cellsEstrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGFExploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction.Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration.Resuscitation-induced intestinal edema and related dysfunction: state of the science.Linking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF.Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissuesTenascin-C and mechanotransduction in the development and diseases of cardiovascular systemGPER Mediates Non-Genomic Effects of Estrogen.Protective effect of statin therapy on connective tissue growth factor induction by diabetes in vivo and high glucose in vitro.Insulin-like growth factor-I regulates GPER expression and function in cancer cells.Stretch-inducible expression of connective tissue growth factor (CTGF) in human osteoblasts-like cells is mediated by PI3K-JNK pathway.Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis.Actin-dependent regulation of connective tissue growth factor.The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells.Cell type-specific regulation of CCN2 protein expression by PI3K-AKT-FoxO signaling.NF-κB mediated miR-26a regulation in cardiac fibrosis.Gene expression analysis reveals an angiogenic profile in uterine leiomyoma pseudocapsuleCyclic Mechanical Stretch Up-regulates Hepatoma-Derived Growth Factor Expression in Cultured Rat Aortic Smooth Muscle Cells.miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.
P2860
Q24644869-55394C8D-1FEE-4B2A-90E5-931C8C361808Q24650762-AA81509E-2774-41A5-AC80-E508F27A46BAQ24683749-72FB0460-4D27-4659-AC49-6387D3D79272Q28579148-DDA52218-B825-40FB-8564-A6EACDFC6A64Q33778029-848F52CF-8C35-4CF5-B317-EC9D67F2BD54Q33872978-21A5BD70-49A4-4BF0-A075-C31ED4C237C9Q34034646-DB872055-4176-41CA-8044-4C2870255E83Q34696040-B1322AA9-6E06-4FE0-9286-3D49B84EDF94Q35067766-FD7E9D8D-A036-4211-8337-334B9141C0B1Q35325935-7D408FE4-7EAD-4356-A461-2516C3BF3928Q35679510-87F79126-F626-4257-8C14-5EBDE087CAF9Q36418892-234D737C-4DA7-481D-BEEC-197ABC89AFC0Q36685242-8445D4C3-AEBF-49C3-8730-98AAACEA55C1Q36849440-27A30545-83A6-4218-B684-2D1053EB473BQ37004735-BFA9CE90-8C68-4DF5-BF2A-1974F05C9E71Q37018256-A377FB23-FD41-4632-8874-812B2C5C9B99Q37096498-C4414352-16AC-440A-9F61-317F0C81279CQ37133153-024D205E-D23C-4997-8CA8-E1BDC304F320Q37133680-830C566F-BB9B-466E-969B-5D3DBEBE78DEQ37371749-60486375-3A14-4880-ADD1-6AF6422B5C0FQ37635765-A7E3D41D-CE65-4FE6-AAEA-5D799AD568FDQ37644080-FE0DAB22-E2A1-4360-944A-C35F78726923Q37723809-1FDB6254-ED08-46E2-9895-B06D700011D9Q38097283-ADB81496-058A-43AE-9FCC-4496090861EFQ38239651-2ECC7FCF-0212-4464-947F-777D384E31CFQ38818348-D076FBBD-4039-4FE4-9B29-F894825069E3Q39066860-24685F76-10DB-4232-A058-1A67BD013796Q39376878-EEB66C66-43A7-4E1E-8D63-354A839039E0Q39484868-1FBD5B81-9FA9-41A7-85E5-329A741B4C7BQ39629598-7080BA26-D936-47C9-9B71-246C51E195B5Q40184484-7015A74F-F385-4A12-881B-C6154FA4081CQ40298927-6F8C3C06-4421-4BD4-8F70-D6B4EABDAED0Q42085271-BCFEDDCF-E3EE-4D94-A3E9-5A53A30F5FCDQ46054688-02307104-5B35-426D-81E5-96E2791241AAQ53102062-C00564D9-C1D9-40C0-ADF7-CE76A4DD836AQ54125165-9F63E9F4-661D-420B-980D-286EDE2CA046Q55340090-C8120E3E-6C8F-4283-A0FE-96C41B42DA33
P2860
Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Mechanical stretch modulates t ...... tion and NF-kappaB activation.
@en
type
label
Mechanical stretch modulates t ...... tion and NF-kappaB activation.
@en
prefLabel
Mechanical stretch modulates t ...... tion and NF-kappaB activation.
@en
P2093
P2860
P356
P1476
Mechanical stretch modulates t ...... tion and NF-kappaB activation.
@en
P2093
P2860
P304
20608-20622
P356
10.1074/JBC.M600214200
P407
P577
2006-05-16T00:00:00Z