Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.
about
Epigenetic changes during cell transformationSmall molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.RREB1 transcription factor splice variants in urologic cancer.Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder.Conditioned medium from Ad-IFN-alpha-infected bladder cancer and normal urothelial cells is cytotoxic to cancer cells but not normal cells: further evidence for a strong bystander effectCell cycle control and DNA damage response of conditionally immortalized urothelial cells.Distinct microRNA alterations characterize high- and low-grade bladder cancerCharacterization of ductal carcinoma in situ cell lines established from breast tumor of a Singapore Chinese patient.FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.Cross-contamination of a UROtsa stock with T24 cells--molecular comparison of different cell lines and stocksExpression of NRG1 and its receptors in human bladder cancer.Early RB94-produced cytotoxicity in cancer cells is independent of caspase activation or 50 kb DNA fragmentation.P16/p53 expression and telomerase activity in immortalized human dental pulp cells.Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific MannerDetection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria.The human urothelial tight junction: claudin 3 and the ZO-1α(+) switch.IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma.An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast CancerPIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma.Immortalized functional endothelial progenitor cell lines from umbilical cord blood for vascular tissue engineering.Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid SynthesisPutative tumour suppressor gene necdin is hypermethylated and mutated in human cancerFibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer.Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine.Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes.The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial Tumors.Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors.Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms.An integrated genomic, transcriptional and protein investigation of FGFRL1 as a putative 4p16.3 deletion target in bladder cancer.Oncogenic FGFR3 gene fusions in bladder cancer.Expression profiling of G-protein-coupled receptors in human urothelium and related cell lines.An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor.Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer.Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.Inhibitor of differentiation 1 (ID1) promotes cell survival and proliferation of prostate epithelial cells.Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner.Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon alpha: possible use as a surrogate marker.Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells.
P2860
Q27002968-8324101B-D621-4A65-AEB3-54D5DA0712A2Q27851612-6E4EAA5F-4026-404D-8F43-91EA6EEFD84DQ30426139-15BE43AD-CB0B-49B6-B8D5-CD9BC80FEE3AQ30981767-E0E19BBD-038B-476B-BF74-DB30BBF865E2Q33778591-D551909D-1BB0-4348-81B3-DEA98D373823Q33804387-BD9DACD0-797E-4426-AB28-E66C81EE749BQ33815979-E64E8055-43A0-428F-AF96-435B9F0EF552Q33854463-39149D5A-DBD5-4115-89E7-8BE461871342Q34253375-8F78516C-4724-4F03-AF61-FDF7A909ACDAQ34305855-D72C23FE-B4DE-46B2-9100-43E4CABC0709Q34585359-14B5E3D7-1966-4DEF-A923-6EBBCD3D72EAQ34731286-70682022-FBDD-43C0-AA8E-AB7E8A6772D2Q34745805-DA000610-A968-4ABA-B207-444802E9912DQ34953231-460DEEA9-81E0-4435-A612-75D22EAAC1F4Q35694629-C46E6D69-CCFA-41B4-9623-4105861DA41BQ35702383-2BCAA889-A9C6-490A-A443-E4EF63AE3461Q35832304-BAD98E07-F9BB-4515-B325-D16955FCA553Q35933212-23722E2F-237F-4536-AA89-ABBE342BCC8DQ35987440-07D92E1F-57F4-4ECA-9CB8-B52266D6734DQ36051976-CBAC95AF-AA69-4F31-98D5-FAB59BCBB145Q36087843-2FF575A5-E9AA-4163-AAA5-FAB91C691572Q36353200-E8A26C93-C176-4BC5-A0CB-EFE2D4BC9172Q36642643-33D93401-472E-4B57-A9CA-40332C653EE1Q36747368-B73F2567-4A6C-4FAA-942C-BB626855989EQ37331829-904CA333-2A2D-4512-B807-02EF5134F9B9Q37555069-48FE8492-90A1-46DC-8573-537136FAA491Q37649062-0CF036DB-3E77-4BBB-B731-23D5C74CCDE1Q38723756-3BBC5DBF-0CCB-413F-9EB9-040308B6F93EQ38973685-EF887790-3CD6-4426-920F-FDE50D104865Q39137809-0938C522-AA5A-4A34-A795-E755B303B1F9Q39138319-4B24ED21-CE82-4739-BA81-BE80DA7A19ADQ39240290-21C7BF9F-3F8F-4D6B-B66C-CEF3FD82CB4CQ39355203-2D5FCB8E-686A-4B2D-ADE5-D00315C5813EQ39623151-76DFC6FF-082F-4658-A9B1-35C8F8E9DD0DQ39648727-047F035D-B211-434E-AE18-91EDF6A480F8Q39671016-E8B17D0E-C80C-4839-954A-9B166512ECE3Q39734867-292B587B-363C-4851-8003-DACA05C4E127Q39800120-BDC54BFC-6927-44A6-ABF4-EC00F1092220Q39886859-291B50E9-6AFE-47BC-B3B5-2060E6CC0C71Q39958711-D97DB64C-6680-466A-B233-E90DF204F4C5
P2860
Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Expression of hTERT immortalis ...... ivation of the p16/Rb pathway.
@en
type
label
Expression of hTERT immortalis ...... ivation of the p16/Rb pathway.
@en
prefLabel
Expression of hTERT immortalis ...... ivation of the p16/Rb pathway.
@en
P2093
P4510
P356
P1433
P1476
Expression of hTERT immortalis ...... ivation of the p16/Rb pathway.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1209513
P407
P577
2006-04-17T00:00:00Z
P5875
P6179
1013769234