Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes.
about
Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombinationMicrobial antigenic variation mediated by homologous DNA recombinationHoming endonucleases: DNA scissors on a missionCharacterization of Rad51 from apicomplexan parasite Toxoplasma gondii: an implication for inefficient gene targetingMicrohomology-mediated and nonhomologous repair of a double-strand break in the chloroplast genome of ArabidopsisAntigenic variation in African trypanosomes.Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major.DNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum.DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes.Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation.CRISPR/Cas9-Induced Disruption of Paraflagellar Rod Protein 1 and 2 Genes in Trypanosoma cruzi Reveals Their Role in Flagellar Attachment.Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining MechanismTrypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics.Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.Efficient gene replacements in Toxoplasma gondii strains deficient for nonhomologous end joiningA yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome.DNA breaks as triggers for antigenic variation in African trypanosomes.Subtelomeric I-SceI-Mediated Double-Strand Breaks Are Repaired by Homologous Recombination in Trypanosoma cruzi.Chromatin and nuclear organization in Trypanosoma cruzi.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Molecular mechanisms underlying the control of antigenic variation in African trypanosomesMolecular scissors for in situ cellular repair.Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control.DNA double-strand breaks and telomeres play important roles in trypanosoma brucei antigenic variation.Characterization of a Trypanosoma brucei Alkb homolog capable of repairing alkylated DNAGenome Editing by CRISPR/Cas9: A Game Change in the Genetic Manipulation of Protists.Elongator protein 3b negatively regulates ribosomal DNA transcription in african trypanosomesTrypanosomal histone γH2A and the DNA damage response.Microhomology-mediated deletion and gene conversion in African trypanosomes.Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei.Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches.CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani.Homologous Recombination in Protozoan Parasites and Recombinase InhibitorsPeptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei.Structural and Biochemical Characterization of Poly-ADP-ribose Polymerase from Trypanosoma bruceiTrypanosoma brucei TIF2 suppresses VSG switching by maintaining subtelomere integrity.Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei.Optimized CRISPR-Cas9 Genome Editing for Leishmania and Its Use To Target a Multigene Family, Induce Chromosomal Translocation, and Study DNA Break Repair Mechanisms.
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P2860
Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Sequence homology and microhom ...... epair in African trypanosomes.
@en
type
label
Sequence homology and microhom ...... epair in African trypanosomes.
@en
prefLabel
Sequence homology and microhom ...... epair in African trypanosomes.
@en
P2860
P356
P1476
Sequence homology and microhom ...... epair in African trypanosomes.
@en
P2093
Richard McCulloch
P2860
P304
P356
10.1093/NAR/GKN104
P407
P577
2008-03-11T00:00:00Z