CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity.
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Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapyCYP3A4 and CYP3A5 genotyping by PyrosequencingGenetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic reviewPolymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapyPersonalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicineFunctionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping testsPolymorphisms of CYP2A6 and its practical consequencesComparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variantsComparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencingAdvances in pharmacogenetics and pharmacogenomics.Cancer therapy and polymorphisms of cytochromes P450.Pharmacogenetic diagnostics of cytochrome P450 polymorphisms in clinical drug development and in drug treatment.Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.Fatal methadone toxicity: potential role of CYP3A4 genetic polymorphism.Pharmacogenetics and antiepileptic drugs.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Cytochrome P450 polymorphisms and response to antipsychotic therapy.Structure-activity relationship for human cytochrome P450 substrates and inhibitors.Pharmacogenetics of the major polymorphic metabolizing enzymes.Pharmacogenomics: marshalling the human genome to individualise drug therapyPharmacogenomic considerations in drug delivery.Population pharmacokinetics of telapristone (CDB-4124) and its active monodemethylated metabolite CDB-4453, with a mixture model for total clearance.From pharmacokinetics to pharmacogenomics: a new approach to tailor immunosuppressive therapy.Frequency of C3435T single nucleotide MDR1 genetic polymorphism in an Asian population: phenotypic-genotypic correlates.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.Cytochrome P450 3A polymorphisms and immunosuppressive drugs.Overview of the pharmacogenetics of HIV therapy.Clinical implications of CYP3A polymorphisms.Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipientsPopulation pharmacokinetics of unbound and total drug concentrations following intravenously administered carbamazepine in elderly and younger adult patients with epilepsy.Past and future applications of CYP450-genetic polymorphisms for biomonitoring of environmental toxicants.Pharmacogenetics of the constitutive androstane receptor.Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update.Interindividual variability of methadone response: impact of genetic polymorphism.Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.Pharmacogenomics of CYP3A: considerations for HIV treatment.Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patientsGender and interindividual variability in pharmacokinetics.Finasteride metabolism and pharmacogenetics: new approaches to personalized prevention of prostate cancer.
P2860
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P2860
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
CYP3A4 allelic variants with a ...... th altered catalytic activity.
@en
type
label
CYP3A4 allelic variants with a ...... th altered catalytic activity.
@en
prefLabel
CYP3A4 allelic variants with a ...... th altered catalytic activity.
@en
P2093
P356
P1476
CYP3A4 allelic variants with a ...... th altered catalytic activity.
@en
P2093
Elizondo G
Gonzalez FJ
P356
10.1067/MCP.2000.104391
P407
P577
2000-01-01T00:00:00Z