Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.
about
DNA mismatch repair: molecular mechanism, cancer, and ageingMagnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutSUsing stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation.Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.Mechanism of MutS searching for DNA mismatches and signaling repairChemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli.Saccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair.Mre11-Rad50 complex crystals suggest molecular calisthenics.Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS.Base-flipping mechanism in postmismatch recognition by MutS.Saccharomyces cerevisiae MSH2-MSH3 and MSH2-MSH6 complexes display distinct requirements for DNA binding domain I in mismatch recognition.Specialized mismatch repair function of Glu339 in the Phe-X-Glu motif of yeast Msh6Deciphering the mismatch recognition cycle in MutS and MSH2-MSH6 using normal-mode analysis.Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.Recognition of damaged DNA: structure and dynamic markers.Modern aspects of the structural and functional organization of the DNA mismatch repair system.Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair.Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypesStructural and functional analysis of the MutS C-terminal tetramerization domain.Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes.The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair.Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates.MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions.Gene silencing by H-NS from distal DNA site.
P2860
Q24647002-871CDBED-C5F6-4D3C-97AF-54E2473345D9Q27659930-314B09D5-D96A-4BFC-ADE5-99DDD00C6BB8Q27678892-FE87C8C0-0A96-400F-B103-5EA8213F6598Q28264548-90BC3680-9C08-4F8B-B491-86E4250972AAQ28756121-E0FF91F6-2FF5-45B8-B19E-44A6E5563F39Q30500132-FB6A0BCE-F5B9-4160-A4B8-8232F207ACA9Q33640393-6E5D68C7-F73E-43C3-9673-A3B117AB2E63Q35256261-10C4F386-3CCD-4012-A16B-7722C66EA6E3Q35259130-E1491326-5B1D-40EA-A8A9-22A336C4393AQ35512872-577048FB-D4F2-4C5E-9191-6D53AD377C9CQ35653058-759544E5-13F1-4E46-9748-865ED5E56925Q35728306-84B89CBE-7492-4FA8-898E-3243E8EC7B48Q35885592-C78DDFFF-DF2D-4867-A521-6BC25750A53AQ37210972-2D1B6BF2-2EC7-45EA-AEF8-9B49703DBD9EQ38005951-3176DE43-F1CB-4BE6-B226-42205B93D122Q38168515-95A7A5F9-2670-4962-A3BC-4E3239849B6EQ38254881-CA821A6A-82FE-48CF-9879-EA6BA0A94D9AQ38739461-A091AA80-E89C-43D9-BAFC-2001E8CF0E8BQ39115482-0CD93C59-8CFB-4D5E-BC86-E9FF0B327ED8Q40124687-652FBD00-C3FD-40A0-9B8E-D761BD5BF2A4Q41860625-D2388693-D126-4582-85D9-2FE3225803DEQ42190109-009E5D44-1A32-4438-B3F4-46C380D21FE2Q42409924-7119D63F-1DD7-4E09-B517-6478868DB044Q45458727-F31302EB-148D-4A20-8BF6-18B0351B0C16Q54329564-DC8DBCBA-1885-444E-96C8-71FDEC2D3416
P2860
Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Dual role of MutS glutamate 38 ...... n the authorization of repair.
@en
type
label
Dual role of MutS glutamate 38 ...... n the authorization of repair.
@en
prefLabel
Dual role of MutS glutamate 38 ...... n the authorization of repair.
@en
P2093
P2860
P356
P1433
P1476
Dual role of MutS glutamate 38 ...... in the authorization of repair
@en
P2093
Alexander Fish
Dubravka Georgijevic
Ganesh Natrajan
Herrie H K Winterwerp
Joyce H G Lebbink
Niels de Wind
P2860
P304
P356
10.1038/SJ.EMBOJ.7600936
P407
P50
P577
2006-01-12T00:00:00Z