about
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibilitySilencing disease genes in the laboratory and the clinicGeneration of Novel Hybrid Aptamer-Molecularly Imprinted Polymeric NanoparticlesEnergetically important C-H···F-C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity.Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencingEnhancer RNA facilitates NELF release from immediate early genesAntisense and antigene inhibition of gene expression by cell-permeable oligonucleotide-oligospermine conjugates.Chemically modified siRNA: tools and applications.Chemical modification of siRNA.Synthesis and biological properties of triazole-linked locked nucleic acid.Improvement of DNA recognition through molecular imprinting: hybrid oligomer imprinted polymeric nanoparticles (oligoMIP NPs).2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.Locked nucleic acid: tighter is different.Oligonucleotide therapeutics: chemistry, delivery and clinical progress.Synthesis and conformational analysis of 2'-fluoro-5-methyl-4'-thioarabinouridine (4'S-FMAU).Efficient gene silencing in brain tumors with hydrophobically modified siRNAs.2′F-Arabinonucleic acids (2′F-ANA) — History, properties, and new frontiersStudies on the hydrolytic stability of 2'-fluoroarabinonucleic acid (2'F-ANA)Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in VivoSingle-Stranded Silencing RNAs: Hit Rate and Chemical ModificationNext-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene SilencingNucleic Acid Therapeutics for Neurological Diseases
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jonathan K Watts
@ast
Jonathan K Watts
@en
Jonathan K Watts
@es
Jonathan K Watts
@nl
Jonathan K Watts
@sl
type
label
Jonathan K Watts
@ast
Jonathan K Watts
@en
Jonathan K Watts
@es
Jonathan K Watts
@nl
Jonathan K Watts
@sl
prefLabel
Jonathan K Watts
@ast
Jonathan K Watts
@en
Jonathan K Watts
@es
Jonathan K Watts
@nl
Jonathan K Watts
@sl
P106
P21
P31
P496
0000-0001-5706-1734