One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element.
about
HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoterLoss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscleActivation and activities of the p53 tumour suppressor proteinAcetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosisAnalysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.Noncanonical DNA motifs as transactivation targets by wild type and mutant p53A p53-dependent promoter associated with polymorphic tandem repeats controls the expression of a viral transcript encoding clustered microRNAsA p53-Pax2 pathway in kidney development: implications for nephrogenesis.Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.The complex interactions of p53 with target DNA: we learn as we go.Activity of the Ste20-like kinase, SLK, is enhanced by homodimerization.p53 and p73 display common and distinct requirements for sequence specific binding to DNAHypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide.Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect.Identification of a p53 response element in the promoter region of the hMSH2 gene required for expression in A2780 ovarian cancer cells.Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter.Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest.Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53.A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions.A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1.Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.p53 down-regulates human bradykinin B1 receptor gene expression.Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation.Isolation and characterization of sixteen novel p53 response genes.Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner.p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression.Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants.Late resistance to adenoviral p53-mediated apoptosis caused by decreased expression of Coxsackie-adenovirus receptors in human lung cancer cells.Retinol, at concentrations greater than the physiological limit, induces oxidative stress and apoptosis in human dermal fibroblasts.p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay.The Mammalian Hairless Protein as a DNA Binding Phosphoprotein.
P2860
Q24292041-A2A5B7CA-4EF9-4E62-9F28-A3F57CB4DFA8Q28273548-A1BC3887-8145-4DB1-AFCA-38B2D8D233A6Q28366563-E83F63B9-02F9-4B6C-80EF-5122DA21E62FQ30435978-581F4F87-DF6E-42B9-8242-D146E627C6FBQ33183660-C5F58A1D-4ABD-441A-9624-BF627D6BFAABQ33361623-88FEE414-77CF-42E1-8135-CF8EDEBB75D6Q34210459-95ABCAA8-A150-4574-BF6D-D702003DFA69Q34416207-360AF148-A957-4765-8E57-247859BBA0F9Q34443272-EE0AD272-EDB5-4E01-AF6C-A498C1943007Q34651573-61223B4C-8699-473B-9FCE-4A443C75640FQ35191541-59E271B7-8168-4EAD-9CC7-493D0E2B9371Q35216773-F61B28EE-EBB8-4630-B723-5B6F287C6C7FQ35646680-D010F757-5A60-4486-BC56-7003F4F5EEA3Q37350632-C9184A8E-B9CF-4E79-8385-EDEB622B4022Q38292772-24037724-B978-4CE8-9081-46A048031A08Q38300890-6D9640F7-47DE-4ED8-91F3-7E1CDE4D01E7Q39615561-3ECEFF6E-9B79-4C15-9E2D-E99839D9228CQ39687319-E7F416A4-DCC5-4BEE-9D73-7F798960DFBAQ39935350-8FC0CB8B-18EC-4C1F-9323-D35C47937A74Q40138858-F20D0735-F063-4243-BA38-67AA158222B5Q40711394-F13B0DB2-427A-484D-BAD9-B43AAC0CD047Q40744476-EDCA9D4A-0BA4-4312-A8C4-0D53B9040F7DQ40794489-9AF33E01-7ECF-4DF3-8F87-E68B6285D328Q40799379-13B07279-7297-4953-AD2D-26D4066D1B1BQ40808379-89D87144-5C4C-44EC-BA92-80FB8AEBD563Q40858501-2333454D-9139-4BAC-9F43-EFDC3474DB2AQ40889690-C54DDE76-218A-4CC3-B9B5-5C908C7179F9Q42660335-54368671-6A5F-4122-BE0F-4B1C4A60BF23Q43652223-E80C2644-AF63-4142-832E-897A01EA6D7FQ43938775-EDD5CE59-2A10-4A58-AED6-30141B2C3160Q44791885-205D4454-B8BC-44EA-9DA3-330D2844094DQ45876572-85BCC93D-B115-40A9-8C62-45F8B2FAEA83Q48650413-FCDAE71E-2FCC-4B76-9A6B-A2DBA285A2CA
P2860
One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
One mechanism for cell type-sp ...... d by the p53 response element.
@en
type
label
One mechanism for cell type-sp ...... d by the p53 response element.
@en
prefLabel
One mechanism for cell type-sp ...... d by the p53 response element.
@en
P356
P1476
One mechanism for cell type-sp ...... d by the p53 response element.
@en
P2093
Manfredi JJ
Thornborrow EC
P304
33747-33756
P356
10.1074/JBC.274.47.33747
P407
P577
1999-11-01T00:00:00Z