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Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping EfficiencyPip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice.The biogenesis and characterization of mammalian microRNAs of mirtron origin.Artificial mirtron-mediated gene knockdown: functional DMPK silencing in mammalian cellsHexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice.Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease.Identification and Characterization of an eIF4e DNA Aptamer That Inhibits Proliferation With High Throughput Sequencing.Identification of a novel muscle targeting peptide in mdx mice.Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties.Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.Optimization of peptide nucleic acid antisense oligonucleotides for local and systemic dystrophin splice correction in the mdx mouse.Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7.Functional VEGFA knockdown with artificial 3'-tailed mirtrons defined by 5' splice site and branch point.Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science.A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapyDiaphragm rescue alone prevents heart dysfunction in dystrophic miceCa2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular storesSystemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology
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description
researcher
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wetenschapper
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հետազոտող
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name
Yiqi Seow
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Yiqi Seow
@en
Yiqi Seow
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Yiqi Seow
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Yiqi Seow
@sl
type
label
Yiqi Seow
@ast
Yiqi Seow
@en
Yiqi Seow
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Yiqi Seow
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Yiqi Seow
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Yiqi Seow
@ast
Yiqi Seow
@en
Yiqi Seow
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Yiqi Seow
@nl
Yiqi Seow
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P106
P1153
25723626400
P31
P496
0000-0001-7040-3006