Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.
about
Cationic phosphoramidate -oligonucleotides efficiently target single-stranded DNA and RNA and inhibit hepatitis C virus IRES-mediated translationReal time detection of DNA.RNA hybridization in living cellsMaking drugs out of oligonucleotides: a brief review and perspective.DNA as therapeutics; an update.Gene therapy for infectious diseasesEffect of 2'-O-methyl antisense ORNs on expression of thymidylate synthase in human colon cancer RKO cells.Antisense oligonucleotides in solution or encapsulated in immunoliposomes inhibit replication of HIV-1 by several different mechanisms.Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries.A brief history, status, and perspective of modified oligonucleotides for chemotherapeutic applications.Sub-cellular trafficking and functionality of 2'-O-methyl and 2'-O-methyl-phosphorothioate molecular beacons.Anomeric inversion (from beta to alpha) in methylphosphonate oligonucleosides enhances their affinity for DNA and RNA.Novel antisense oligonucleotides containing hydroxamate linkages: targeted iron-triggered chemical nucleases.Differential effects of PKA-controlled CaMKK2 variants on neuronal differentiationOligodeoxynucleoside phosphoramidates (P-NH2): synthesis and thermal stability of duplexes with DNA and RNA targetsInvestigation of some properties of oligodeoxynucleotides containing 4'-thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity.alpha-Oligodeoxyribonucleotide N3'-->P5' phosphoramidates: synthesis and duplex formationStructural properties of DNA:RNA duplexes containing 2'-O-methyl and 2'-S-methyl substitutions: a molecular dynamics investigation.RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers.L-DNAs as potential antimessenger oligonucleotides: a reassessment.Modulation of oligonucleotide duplex and triplex stability via hydrophobic interactions.Development of antisense therapeutics. Implications for cancer gene therapy.Physico-chemical and biological properties of antisense phosphodiester oligonucleotides with various secondary structures.FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets.Chimeric alpha-beta oligonucleotides as antisense inhibitors of reverse transcription.Electrochemical detection of nucleic acids using pentaferrocenyl phosphoramidate α-oligonucleotides
P2860
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P2860
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.
@en
type
label
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.
@en
prefLabel
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.
@en
P2093
P356
P1476
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents
@en
P2093
B S Sproat
I Lefebvre
J L Imbach
P304
P356
10.1021/JM00054A013
P407
P577
1993-01-01T00:00:00Z