First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.
about
GAGE: generally applicable gene set enrichment for pathway analysisSqualene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II diseaseAggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation.Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors.Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics.The balance of cell surface and soluble type III TGF-β receptor regulates BMP signaling in normal and cancerous mammary epithelial cells.Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.BMPR2 expression is suppressed by signaling through the estrogen receptor.Induction of Smad1 by MT1-MMP contributes to tumor growth.The soluble form of BMPRIB is a novel therapeutic candidate for treating bone related disorders.Genome-wide approaches for identification of nuclear receptor target genes.MicroRNA variants as genetic determinants of bone massWhole genome expression analysis for biologic rational pathway modeling: application in cancer prognosis and therapy prediction.Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxane-anthracycline chemotherapyGenetic variation in bone morphogenetic proteins and breast cancer risk in hispanic and non-hispanic white women: The breast cancer health disparities study.Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways.ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.The multiple facets of dermcidin in cell survival and host defense.Bi-directional roles of bone morphogenetic proteins in cancer: another molecular Jekyll and Hyde?Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition.Combinatorial use of bone morphogenetic protein 6, noggin and SOST significantly predicts cancer progression.Bone morphogenetic protein 4 (BMP4) is required for migration and invasion of breast cancer.Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance.Antiproliferative and protein kinase binding activities of Some N6, 5'-bis-ureido 5'-amino-5'-deoxyadenosine derivatives.Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer.[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives.Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.Bone Morphogenetic Proteins.
P2860
Q24645628-C8714E12-E0A0-40D5-8C8E-F7945887E819Q24655384-BF091D9F-D612-4A42-B940-A77EB50C89CBQ30487367-0436FA10-EC5A-4D27-9AFD-868C45C4FF4BQ33505662-2EF6F191-5E49-40D3-B8B7-C9DFC20AEFD4Q34140962-98F1891F-88D9-4BA4-A2DF-1EE999853C25Q34346737-E3F250AC-93DE-4C5A-BF45-28185E8768B0Q35075436-1E399372-7A85-48FF-ACAB-D52DA33F1446Q35778924-CCF1466D-7806-4D2F-BAD6-7937C61C527FQ35848094-8E5A8E9C-6A29-48A9-88C7-A62558186AB8Q36157381-E7C3EA97-7C60-4F54-96EB-E5A6C3232FD5Q36432535-152CDA3D-23C9-44C2-80A1-4D97745C1A8CQ36544557-27AE0A26-7D93-4DAE-AD9C-B483A187FA3AQ36586312-755E776E-1920-4145-950D-FCC3ED8020D8Q36615223-F4143DAC-5337-4DA4-A5B8-E339BA41E56BQ36782582-0D55D666-8461-4623-AED9-6C7BBAF6C53DQ36841890-44E1CC0D-4534-4837-AB9E-EAAB8268A952Q37001447-20B6A6AA-4C9A-418A-A2E9-F8D0ECD260D5Q37084581-3924DF63-5CA7-46D2-9F61-826CE3535AB6Q37353829-DEC6A17D-7B95-458D-ACFB-BFFC16235398Q37997876-A644BED0-EF31-487E-A564-EB5B29619932Q38115632-A69ABD48-F27D-4AAA-B1C5-3EE8E6CF8961Q38928611-AC2B4868-2E1D-497D-8BE3-C7857961DB8AQ39390484-6C968E90-14A6-4008-B99F-44DB51ECEFB8Q39428841-658420BF-C93B-4C97-A780-57ECFF76444AQ39451397-4A86400C-3345-4A05-B242-51B34112F090Q39735284-AED7EB06-B02A-4069-9491-C46F5FC46E8DQ40725954-61EAFE2E-405A-4151-B867-24C807E3DD10Q42951218-9C780C94-7541-43F8-8B2A-309B06A91290Q47250561-C4259D01-3854-4AB5-89AB-1085680965CFQ51706240-75800DB2-3A37-491B-AA41-6250A4D3D7B1Q51724862-C3E5972D-ADCB-4A58-AB2A-295AB2444325
P2860
First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
First evidence supporting a po ...... ceptor-positive breast cancer.
@en
type
label
First evidence supporting a po ...... ceptor-positive breast cancer.
@en
prefLabel
First evidence supporting a po ...... ceptor-positive breast cancer.
@en
P2093
P356
P1476
First evidence supporting a po ...... eceptor-positive breast cancer
@en
P2093
Birgit Schittek
Christian August
Horst Buerger
Jens Packeisen
Mike W Helms
Werner Boecker
P2860
P304
P356
10.1002/PATH.1785
P577
2005-07-01T00:00:00Z