A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.
about
Modulation of the Coagulation Cascade Using AptamersSelection and characterization of a DNA aptamer inhibiting coagulation factor XIa.Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamersProbing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation.Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant.Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40.Translation and Clinical Development of Antithrombotic Aptamers.Aptamers: problems, solutions and prospects.Rapid Complexation of Aptamers by Their Specific Antidotes.Trends in the Design and Development of Specific Aptamers Against Peptides and Proteins.Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer.Deciphering Conformational Changes Associated with the Maturation of Thrombin Anion Binding Exosite I.Discovery methods of coagulation-inhibiting drugs.Effect of Chemical Modifications on Aptamer Stability in Serum.A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release.Aptamer Therapeutics in Cancer: Current and Future.
P2860
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P2860
A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
A high affinity, antidote-cont ...... eration and thrombin activity.
@en
type
label
A high affinity, antidote-cont ...... eration and thrombin activity.
@en
prefLabel
A high affinity, antidote-cont ...... eration and thrombin activity.
@en
P2093
P2860
P1476
A high affinity, antidote-cont ...... neration and thrombin activity
@en
P2093
B A Sullenger
F C Church
K M Bompiani
P2860
P304
P356
10.1111/J.1538-7836.2012.04679.X
P577
2012-05-01T00:00:00Z