Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-beta signaling in cultured scleroderma fibroblasts.
about
Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanismsThrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism.Decreased astrocytic thrombospondin-1 secretion after chronic ammonia treatment reduces the level of synaptic proteins: in vitro and in vivo studiesApoptosis modulation as a promising target for treatment of systemic sclerosis.Systemic sclerosis: a prototypic multisystem fibrotic disorder.Impaired expression of thrombospondin-1 in eyes with age related macular degeneration.Plasmin triggers a switch-like decrease in thrombospondin-dependent activation of TGF-β1.Scar wars: is TGFbeta the phantom menace in scleroderma?Update on pathophysiology of scleroderma with special reference to immunoinflammatory events.Molecular analysis of early host cell infection by Trypanosoma cruzi.Establishment and characterization of scleroderma fibroblast clonal cell lines by introduction of the hTERT gene.The impact of Fli1 deficiency on the pathogenesis of systemic sclerosisFuture treatments in systemic sclerosis.The Role of TGF-β Receptors in Fibrosis.Transforming growth factor β--at the centre of systemic sclerosis.Bosentan reverses the pro-fibrotic phenotype of systemic sclerosis dermal fibroblasts via increasing DNA binding ability of transcription factor Fli1.Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissuesRegulation of epithelial cell proliferation by bronchial fibroblasts obtained from mild asthmatic subjects.Recent advances in the treatment of skin involvement in systemic sclerosis.Transforming growth factor-β in stem cells and tissue homeostasis.Stable RNA interference of host thrombospondin-1 blocks Trypanosoma cruzi infection.Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.Enhanced expression of ephrins and thrombospondins in the dermis of patients with early diffuse systemic sclerosis: potential contribution to perturbed angiogenesis and fibrosis.Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin
P2860
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P2860
Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-beta signaling in cultured scleroderma fibroblasts.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Constitutive thrombospondin-1 ...... tured scleroderma fibroblasts.
@en
type
label
Constitutive thrombospondin-1 ...... tured scleroderma fibroblasts.
@en
prefLabel
Constitutive thrombospondin-1 ...... tured scleroderma fibroblasts.
@en
P2093
P2860
P1476
Constitutive thrombospondin-1 ...... tured scleroderma fibroblasts.
@en
P2093
Hironobu Ihn
Kenichi Yamane
Kunihiko Tamaki
Masatoshi Jinnin
Yoshihide Asano
Yoshihiro Mimura
P2860
P304
P356
10.1016/S0002-9440(10)62362-0
P407
P577
2005-05-01T00:00:00Z