about
IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis.Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice.Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo.Opposing functions of IL-2 and IL-7 in the regulation of immune responses.Interleukin-7: Fuel for the autoimmune attack.Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia.Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG-M and the tumor-associated antigen HTgp-175.Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells.The initial phase of an immune response functions to activate regulatory T cells.Type 1 diabetes alters lipid handling and metabolism in human fibroblasts and peripheral blood mononuclear cells.Increased expression and modulated regulatory activity of co-inhibitory receptors PD-1, TIGIT and TIM-3 in lymphocytes of systemic sclerosis patients.Life and death in effector T cells.A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg.Combining anti-IL-7Rα antibodies with autoantigen-specific immunotherapy enhances non-specific cytokine production but fails to prevent Type 1 DiabetesInduction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo
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description
hulumtues
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wetenschapper
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հետազոտող
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Hans Dooms
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Hans Dooms
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6603383204
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0000-0001-7964-0876