IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation.
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Macropinosomes are Key Players in Early Shigella Invasion and Vacuolar Escape in Epithelial CellsThe IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cellsThe Shigella flexneri type 3 secretion system is required for tyrosine kinase-dependent protrusion resolution, and vacuole escape during bacterial disseminationStructural insights into host GTPase isoform selection by a family of bacterial GEF mimicsStructure of Shigella IpgB2 in Complex with Human RhoA: IMPLICATIONS FOR THE MECHANISM OF BACTERIAL GUANINE NUCLEOTIDE EXCHANGE FACTOR MIMICRYShigella flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron ResonanceThe C-terminus of IpaC is required for effector activities related to Shigella invasion of host cellsHierarchies of host factor dynamics at the entry site of Shigella flexneri during host cell invasion.A functional genomic yeast screen to identify pathogenic bacterial proteinsThe T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals.Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors.Caspase-1 activation via Rho GTPases: a common theme in mucosal infections?Distribution of espM and espT among enteropathogenic and enterohaemorrhagic Escherichia coli.Bacterial factors exploit eukaryotic Rho GTPase signaling cascades to promote invasion and proliferation within their host.The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins.Molecular mechanisms of host cytoskeletal rearrangements by Shigella invasins.The optimal concentration of siRNA for gene silencing in primary cultured astrocytes and microglial cells of ratsThe Shigella type three secretion system effector OspG directly and specifically binds to host ubiquitin for activation.A multifunctional region of the Shigella type 3 effector IpgB1 is important for secretion from bacteria and membrane targeting in eukaryotic cells.Engineering Escherichia coli into a protein delivery system for mammalian cells.Intracellular survival of Shigella.Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion systemType III secretion systems and disease.Mimicking small G-proteins: an emerging theme from the bacterial virulence arsenal.Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countriesSystems-level overview of host protein phosphorylation during Shigella flexneri infection revealed by phosphoproteomics.Perturbation of vacuolar maturation promotes listeriolysin O-independent vacuolar escape during Listeria monocytogenes infection of human cells.Spa15 of Shigella flexneri is secreted through the type III secretion system and prevents staurosporine-induced apoptosis.A new paradigm of bacteria-gut interplay brought through the study of Shigella.Recent insights into Pasteurella multocida toxin and other G-protein-modulating bacterial toxins.Uncivil engineers: Chlamydia, Salmonella and Shigella alter cytoskeleton architecture to invade epithelial cells.Manipulation of host membranes by bacterial effectors.Mimicking GEFs: a common theme for bacterial pathogens.Use of the plaque assay for testing the antibiotic susceptibility of intracellular bacteria.Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics.How Do the Virulence Factors of Shigella Work Together to Cause Disease?EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42.Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.A systematic exploration of the interactions between bacterial effector proteins and host cell membranes.
P2860
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P2860
IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
IpgB1 is a novel Shigella effe ...... via Rac1 and Cdc42 activation.
@en
type
label
IpgB1 is a novel Shigella effe ...... via Rac1 and Cdc42 activation.
@en
prefLabel
IpgB1 is a novel Shigella effe ...... via Rac1 and Cdc42 activation.
@en
P2093
P2860
P356
P1476
IpgB1 is a novel Shigella effe ...... via Rac1 and Cdc42 activation.
@en
P2093
Chihiro Sasakawa
Kenji Ohya
Masato Suzuki
Michinaga Ogawa
Yutaka Handa
P2860
P304
24022-24034
P356
10.1074/JBC.M502509200
P407
P577
2005-04-22T00:00:00Z