Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.
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Identification and characterization of the human orthologue of yeast Pex14pPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importIdentification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammalsThe Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognitionAnalysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assayCharacterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 IN Pex3p as a critical residue for the interactionSolution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scatteringPEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14Hsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.Peroxisome protein import: a complex journeyThe similarity between N-terminal targeting signals for protein import into different organelles and its evolutionary relevancePeroxisomes take shapeA Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into PeroxisomesCharacterization of the interaction between Trypanosoma brucei Pex5p and its receptor Pex14pSaccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.Recognition of peroxisomal targeting signal type 1 by the import receptor Pex5p.Membrane association of the cycling peroxisome import receptor Pex5p.Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteinsThe peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction.Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites.Potential role for Pex19p in assembly of PTS-receptor docking complexesYarrowia lipolytica Pex20p, Saccharomyces cerevisiae Pex18p/Pex21p and mammalian Pex5pL fulfil a common function in the early steps of the peroxisomal PTS2 import pathwayAWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPaseGenetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classesInteraction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p.Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein.Saccharomyces cerevisiae Pex14p contains two independent Pex5p binding sites, which are both essential for PTS1 protein import.Yarrowia lipolytica cells mutant for the peroxisomal peroxin Pex19p contain structures resembling wild-type peroxisomesA PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.Dynamics of the peroxisomal import cycle of PpPex20p: ubiquitin-dependent localization and regulation.Matrix proteins are inefficiently imported into Arabidopsis peroxisomes lacking the receptor-docking peroxin PEX14Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import InteractionsPex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal-receptor docking complex in Pichia pastoris.Redox-regulated cargo binding and release by the peroxisomal targeting signal receptor, Pex5.Regulation of peroxisome dynamics
P2860
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P2860
Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Recombinant human peroxisomal ...... nteraction of PEX5 with PEX14.
@en
type
label
Recombinant human peroxisomal ...... nteraction of PEX5 with PEX14.
@en
prefLabel
Recombinant human peroxisomal ...... nteraction of PEX5 with PEX14.
@en
P2093
P2860
P356
P1476
Recombinant human peroxisomal ...... interaction of PEX5 with PEX14
@en
P2093
P2860
P304
P356
10.1074/JBC.274.9.5666
P407
P577
1999-02-01T00:00:00Z