The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
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A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteinsHrs recruits clathrin to early endosomesThe RCP-Rab11 complex regulates endocytic protein sortingClass III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane trafficStructural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)Kinetic analysis of the interaction of the copper chaperone Atox1 with the metal binding sites of the Menkes proteinThe p97 ATPase associates with EEA1 to regulate the size of early endosomesTranslation of the phosphoinositide code by PI effectorsWortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cellsEndocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related proteinEEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblastsRole of Rab GTPases in membrane traffic and cell physiologyIdentification and structural characterization of FYVE domain-containing proteins of Arabidopsis thaliana.Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis.SeqA protein aggregation is necessary for SeqA function.Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension.Membrane tetheringMolecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.Human Nischarin/imidazoline receptor antisera-selected protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region.Vesicular protein transport.Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi.Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.Membrane recognition and targeting by lipid-binding domains.Phosphoinositides and vesicular membrane trafficPhosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain.A comprehensive map of the toll-like receptor signaling network.Molecular dissection of Rab11 binding from coiled-coil formation in the Rab11-FIP2 C-terminal domain.Mechanistic similarities in docking of the FYVE and PX domains to phosphatidylinositol 3-phosphate containing membranes.SNARE function is not involved in early endosome dockingMolecular analysis of protein-phosphoinositide interactions.The autophagic pathway is actively modulated by phase II Coxiella burnetii to efficiently replicate in the host cell.Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues.A modification switch on a molecular switch: Phosphoregulation of Rab7 during endosome maturationThe Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden.A tethering complex dimer catalyzes trans-SNARE complex formation in intracellular membrane fusion.Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1.The reaction of alpha-crystallin with the cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate) demonstrates close proximity of the C termini of alphaA and alphaB in the native assembly.Unexpected products from the reaction of the synthetic cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP with peptides.Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
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The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
@en
type
label
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
@en
prefLabel
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
@en
P2093
P2860
P1433
P1476
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.
@en
P2093
P2860
P304
P356
10.1042/0264-6021:3380539
P407
P478
338 ( Pt 2)
P577
1999-03-01T00:00:00Z